C6241
Charcoal, Dextran Coated
Sinónimos:
Dextran coated charcoal
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UNSPSC Code:
12141908
EC Number:
231-153-3
NACRES:
NC.07
Servicio técnico
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powder
Quality Level
General description
Charcoal, Dextran Coated is made from acid washed charcoal powder and dextran, molecular weight 64-76kDa, combined in a 10:1 (w/w) ratio.
Application
Charcoal, Dextran Coated has been used:
- as a supplement in cell culture media to test the functioning of androgen receptor
- in the procedure of melatonin radioimmunoassay
- for the preparation of steroid-free human serum
- to reduce the creatinine level in untreated serum.
Biochem/physiol Actions
The use of dextran-coated charcoal makes the immunoassay of insulin in biological fluids simpler and more rapid. In theory, the charcoal coated with dextran will adsorb the free hormone and leave hormones that are bound to a carrier (or antibody). Dextran coated charcoal is used to strip hormones from serum instead of charcoal alone, because there is less loss of protein using dextran coated charcoal.
Other Notes
Dry preparation of dextran-treated charcoal
Clase de almacenamiento
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Contenido relacionado
Modern Methods of Steroid Analysis (2012)
Coated charcoal immunoassay of insulin.
Herbert V
The Journal of Clinical Endocrinology and Metabolism, 25, 1375-1384 (1965)
Multisteroid LC-MS/MS assay for glucocorticoids and androgens, and its application in Addison's disease.
Methlie P
Endocrine Connections (2013)