EHU133151
MISSION® esiRNA
targeting human PPP4R2
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NACRES:
NA.51
UNSPSC Code:
41105324
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Quality Level
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
TTCCTGGAAATTCACCAAGCTATACTGAGAGGTCTAATATAAATGGGCCTGGGACACCCAGGCCACTTAATCGACCAAAGGTTTCTTTGTCAGCCCCCATGACAACAAATGGGTTGCCTGAGAGCACAGACAGCAAAGAGGCAAATTTGCAGCAAAATGAGGAGAAAAATCACAGTGACTCTTCGACCTCTGAATCAGAAGTTTCCTCAGTGAGCCCTTTGAAAAATAAACATCCAGATGAAGATGCTGTGGAAGCTGAGGGGCATGAGGTAAAAAGACTCAGGTTTGACAAAGAAGGTGAAGTCAGAGAAACAGCCAGTCAAACGACTTCCAGCGAAATTTCTTCAGTTATGGTAGGAGAAACAGAAGCATCATCTTCATCTCAGGATAAAGACAAAGATAGCCGTTGTACCCG
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Gene Information
human ... PPP4R2(151987)
General description
MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
Clase de almacenamiento
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
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Pabitra K Parua et al.
Nature communications, 11(1), 4338-4338 (2020-08-30)
Reversible phosphorylation of Pol II and accessory factors helps order the transcription cycle. Here, we define two kinase-phosphatase switches that operate at different points in human transcription. Cdk9/cyclin T1 (P-TEFb) catalyzes inhibitory phosphorylation of PP1 and PP4 complexes that localize