G0897
Genistin
From Glycine max (soybean), ≥95% (HPLC), terminal deoxynucleotidyl transferase (TdT) inhibitor
Sinónimos:
4′,5,7-Trihydroxyisoflavone 7-glucoside, Genistein 7-glucoside, Genistein-7-O-β-D-glucopyranoside, Genistoside, NSC 5112
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Fórmula empírica (notación de Hill):
C21H20O10
Número CAS:
Peso molecular:
432.38
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
64479
Assay:
≥95% (HPLC)
Quality level:
Servicio técnico
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Permítanos ayudarleNombre del producto
Genistin, from Glycine max (soybean), ≥95% (HPLC)
biological source
Glycine max (soybean)
Quality Level
assay
≥95% (HPLC)
solubility
DMSO: 10 mg/mL
storage temp.
−20°C
SMILES string
OC[C@H]1O[C@@H](Oc2cc(O)c3C(=O)C(=COc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O
InChI
1S/C21H20O10/c22-7-15-18(26)19(27)20(28)21(31-15)30-11-5-13(24)16-14(6-11)29-8-12(17(16)25)9-1-3-10(23)4-2-9/h1-6,8,15,18-24,26-28H,7H2/t15-,18-,19+,20-,21-/m1/s1
InChI key
ZCOLJUOHXJRHDI-CMWLGVBASA-N
Application
Genistin has been used for immune reactivity against influenza viruses in vitro and as an internal standard in isoflavones quantification.
Biochem/physiol Actions
Inactive analog of genistein; useful as a negative control for genistein and other tyrosine kinase inhibitors.
Selective inhibitor of mammalian terminal deoxynucleotidyl transferase (TdT), with no measurable effect on mammalian or microbial DNA polymerases.
Features and Benefits
This compound is featured on the Dopamine and Norepinephrine Metabolism and Histamine Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Clase de almacenamiento
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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The phytochemcal profiles of Cudrania cochinchinensis leaf, twig, stem and root were compared by HPLC analysis. It was found that C. cochinchinensis stem extract contained some unknown natural products with potential tyrosinase inhibitory activities. Therefore, the chemical constitutes in extract