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Merck

P0928

Resorufin pentyl ether

≥98% (TLC), Fluorimetric Cytochrome P450 substrate, powder

Sinónimos:

7-Pentyloxy-3-phenoxazone, 7-Pentyloxy-3H-phenoxazin-3-one, O7-Pentylresorufin, Pentoxyresorufin

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Fórmula empírica (notación de Hill):
C17H17NO3
Número CAS:
Peso molecular:
283.32
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12161501
MDL number:
Beilstein/REAXYS Number:
8394939
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Nombre del producto

Resorufin pentyl ether,

assay

≥98% (TLC)

Quality Level

form

powder

solubility

acetonitrile: 0.95- 1.05 mg/mL, clear, orange

storage temp.

2-8°C

SMILES string

CCCCCOc1ccc2N=C3C=CC(=O)C=C3Oc2c1

InChI

1S/C17H17NO3/c1-2-3-4-9-20-13-6-8-15-17(11-13)21-16-10-12(19)5-7-14(16)18-15/h5-8,10-11H,2-4,9H2,1H3

InChI key

ZPSOKQFFOYYPKC-UHFFFAOYSA-N

General description

Resorufin pentyl ether is an analog of resazurin. Resorufin is a redox probe which is colorless and non-fluorescent in its reduced state. On oxidation, it fluoresces red. Resorufin is used widely as an indicator in microbiological media. It can be used to differentiate between actively metabolizing cells and inactive or dead cells.

Application

Resorufin pentyl ether has been used as a substrate to study the effects of Kaempferia parviflora extract on mouse hepatic cytochrome P450 enzymes.

Biochem/physiol Actions

Fluorimetric substrate for cytochrome P450 linked enzymes, CYP2B and CYP2B4.


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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R B van Breemen et al.
Drug metabolism and disposition: the biological fate of chemicals, 26(2), 85-90 (1998-03-28)
An on-line mass spectrometric method has been developed to generate and identify drug metabolites formed by hepatic cytochromes P450. This method, pulsed ultrafiltration-mass spectrometry, may be used for rapid screening of drugs to determine their extent of metabolism by microsomal
Canan Sapmaz et al.
Drug and chemical toxicology, 43(1), 13-21 (2018-05-19)
Morin is a flavonoid which is present in many plants. Endosulfan and 7,12-dimethylbenz[a]anthracene (DMBA) are toxic chemicals that humans are exposed to in their daily lives. In this study, the protective role of morin was investigated in endosulfan and DMBA
Aline Y O Matsuo et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 147(1), 78-84 (2007-09-11)
Wild stocks of Pacific salmon in the Northwestern United States have declined in recent years, and the major factors contributing to these losses include water pollution and loss of habitat. In salmon, sublethal chemical exposures may impact critical behaviors (such