P8087
Monoclonal Anti-Plakoglobin (Catenin γ) antibody produced in mouse
clone 15F11, ascites fluid, buffered aqueous solution
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Acerca de este artículo
Conjugate:
unconjugated
Clone:
15F11, monoclonal
Application:
ARR, ICC, IF, IHC (f), IP, WB
Citations:
16
Servicio técnico
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Permítanos ayudarlebiological source
mouse
Quality Level
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
15F11, monoclonal
form
buffered aqueous solution
mol wt
antigen 85 kDa
contains
15 mM sodium azide
species reactivity
bovine, canine, human
technique(s)
immunocytochemistry: suitable using cultured cells, immunohistochemistry (frozen sections): suitable, immunoprecipitation (IP): suitable, indirect immunofluorescence: 1:1,000 using cultured MDBK cells, microarray: suitable, western blot: 1:2,000 using cultured MDBK cells
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... JUP(3728)
General description
Plakoglobin is a desmosomal protein that regulates developmental signalling in vertebrates. Tyrosine phosphorylation of plakoglobin has been linked to adenocarcinomas . Plakoglobin may function as a tumor suppressor in ovarian and breast cancers .
Immunogen
recombinant chicken plakoglobin.
Application
Monoclonal anti-plakoglobin (catenin γ) antibody is suitable for use in immunocytochemistry (using MDCK cells), immunoprecipitation, and in immunoblotting . The antibody may also be used for immunohistochemistry (frozen sections), microarray, western blot (1:500, using cultured MDBK cells) and indirect immunofluorescence (1:1000, using cultured MDBK cells).
Biochem/physiol Actions
The antibody recognizes the plakoglobin (catenin-γ) molecule (85 kDa and possibly a slightly lower band) by immunoblotting. It does not cross-react with β-catenin. The antibody reacts with plakoglobin in bovines, humans and dogs, but does not react with β catenin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Clase de almacenamiento
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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