PLA0230
Rabbit anti-Beta-catenin Antibody, Affinity Purified
Powered by Bethyl Laboratories, Inc.
Sinónimos:
88kDa, CTNNB, MRD19, armadillo, beta 1, beta 1 (88kD), beta-catenin, catenin (cadherin-associated protein)
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NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ChIP, IHC, IP, WB
Citations:
6
Servicio técnico
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Permítanos ayudarlebiological source
rabbit
Quality Segment
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse
technique(s)
ChIP: 4-30 μg, immunohistochemistry: 1:100- 1:500, immunoprecipitation (IP): 2- 5 μg/mg, western blot: 1:2,000- 1:10,000
accession no.
NP_001895.1
application(s)
research pathology
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
rabbit ... Beta-catenin(1499)
Immunogen
The epitope recognized by PLA0230 maps to a region between residue 760 and 781 of human beta-catenin using the numbering given in entry NP_001895.1 (GeneID 1499).
Physical form
Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide
Other Notes
Beta-catenin plays an integral role in the Wnt signaling pathway and is critical to morphogenic signaling and body axis specification. Beta-catenin exists in complexes with cadherins, transmembrane proteins that mediate cell adhesion. When Wnt-signaling proteins bind their receptors, beta-catenin is stabilized and accumulates in the cell. Translocation of stabilized beta-catenin allows its association with transcription factors and the activation of specific gene expression.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Clase de almacenamiento
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
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