11020AST
Astec® CHIROBIOTIC® V Chiral (5 μm) HPLC Columns
L × I.D. 25 cm × 2.1 mm, HPLC Column
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UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × i.d.:
25 cm × 2.1 mm
Particle size:
5 μm
Matrix active group:
vancomycin phase
Pore size:
100 Å
Matrix:
High-purity silica gel particle platform, fully porous particle
Servicio técnico
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Permítanos ayudarleNombre del producto
Astec® Chirobiotic® V Chiral HPLC Column, 5 μm particle size, L × I.D. 25 cm × 2.1 mm
material
stainless steel column
Quality Level
agency
suitable for USP L88
description
HPLC Column
product line
Astec®
packaging
pkg of 1 ea
manufacturer/tradename
Astec®
parameter
0-45 °C temperature, 241 bar pressure (3500 psi)
technique(s)
HPLC: suitable, LC/MS: suitable
L × I.D.
25 cm × 2.1 mm
matrix
High-purity silica gel particle platform, fully porous particle
matrix active group
vancomycin phase
particle size
5 μm
pore size
100 Å
operating pH range
3.5-7.0
separation technique
chiral
General description
Neutral molecules, amides, acids, esters and amines show considerable enantioselectivity on these vancomycin-based CSPs. A wide variety of secondary and tertiary amines have been separated on the CHIROBIOTIC® V in the polar ionic mode. The CHIROBIOTIC® V has demonstrated many of the separation characteristics of protein-based stationary phases, but with exceptional stability and much higher sample capacity. Some chiral analytes have been resolved that have not been reported separated on any other chiral stationary phase. CHIROBIOTIC® V and V2 differ in their bonding chemistry the pore size of the support particle, giving them different selectivity and preparative capacity.
- Bonded phase: Vancomycin
- Operating pH range: 3.5 - 7.0
- Particle diameter: 5, 10 or 16 μm
- Pore size: 100 Å (CHIROBIOTIC® V) or 200 Å (CHIROBIOTIC® V2)
Legal Information
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
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Sherri L MacLeod et al.
Journal of chromatography. A, 1170(1-2), 23-33 (2007-10-05)
A reversed-phase enantioselective liquid chromatography-tandem mass spectrometry (HPLC-MS-MS) method was developed to measure enantiomer fractions (EF) and concentrations of pharmaceuticals in wastewater. Enantiomer resolution of six beta-blockers (atenolol, metoprolol, nadolol, pindolol, propranolol, and sotalol) along with two selective serotonin re-uptake
Analysis of the enantiomers of citalopram and its demethylated metabolites using chiral liquid chromatography
Kosel, M., et al.
Journal of Chromatography. B, Biomedical Applications, 719 (1-2), 234-238 (1998)
Enantiomeric separation of mirtazapine and its metabolite in rat plasma by reverse polar ionic liquid chromatography using fluorescence and polarimetric detectors connected in series
Rao, R. Nageswara, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 879 (21), 1911-1916 (2011)