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Merck

13023AST

Astec® CHIROBIOTIC® R Chiral (5 μm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

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UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × i.d.:
15 cm × 4.6 mm
Particle size:
5 μm
Matrix active group:
ristocetin A glycopeptide phase
Pore size:
100 Å
Matrix:
high-purity silica gel particle platform, fully porous particle
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Nombre del producto

Astec® Chirobiotic® R Chiral HPLC Column, 5 μm particle size, L × I.D. 15 cm × 4.6 mm

material

stainless steel column

Quality Level

description

HPLC column

product line

Astec®

packaging

pkg of 1 ea

manufacturer/tradename

Astec®

parameter

0-45 °C temperature, 241 bar pressure (3500 psi)

technique(s)

HPLC: suitable, LC/MS: suitable

L × I.D.

15 cm × 4.6 mm

matrix

high-purity silica gel particle platform, fully porous particle

matrix active group

ristocetin A glycopeptide phase

particle size

5 μm

pore size

100 Å

operating pH range

3.5-6.8

separation technique

chiral

General description

CHIROBIOTIC® R, based on the ristocetin A glycopeptide covalently bonded to high purity silica particles, has shown particular applicability to enantiomers of anionic compounds. Selectivity on CHIROBIOTIC® R strongly correlates to the organic modifier, favoring the alcohol-type mobile phases by a large margin.

  • Bonded phase: Ristocetin A
  • Operating pH range: 3.5 - 6.8
  • Particle diameter: 5, 10 or 16 μm
  • Pore size: 100 Å

CHIROBIOTIC FAQs
CHIROBIOTIC Reference Bibliography
Chiral Product Literature

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC


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Enzyme-catalyzed synthesis of (R)- and (S)-3-hydroxy-3-(10-alkyl-10H-phenothiazin-3-yl)propanoic acids
Brem, Jurgen, et al.
Tetrahedron Asymmetry, 21 (3), 365-373 (2010)
Ting Zhou et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1002, 218-227 (2015-09-06)
The chiral inversion has been a concerned issue during the research and development of a chiral drug. In this study, a sensitive chiral liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for determination of salbutamol enantiomers in human plasma and
Diane E Halliwell et al.
Scientific data, 4, 170084-170084 (2017-07-12)
Using a scanning near-field optical microscope coupled to an infrared free electron laser (SNOM-IR-FEL) in low-resolution transmission mode, we collected chemical data from whole cervical cells obtained from 5 pre-menopausal, non-pregnant women of reproductive age, and cytologically classified as normal