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Merck

59353-U

Discovery® C8 (5 µm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

Sinónimos:

C8 Reversed-Phase Chromatography Column

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UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × i.d.:
15 cm × 4.6 mm
Particle size:
5 μm
Matrix active group:
C8 (octyl) phase
Pore size:
180 Å
Matrix:
silica gel, high purity, spherical base material, fully porous particle
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Nombre del producto

Columna para HPLC Discovery® C8, 5 μm particle size, L × I.D. 15 cm × 4.6 mm

material

stainless steel column

Quality Level

agency

suitable for USP L7

product line

Discovery®

feature

endcapped

manufacturer/tradename

Discovery®

packaging

1 ea of

extent of labeling

7.5% Carbon loading

parameter

≤70 °C temp. range, 400 bar pressure (5801 psi)

technique(s)

HPLC: suitable, LC/MS: suitable

L × I.D.

15 cm × 4.6 mm

surface area

200 m2/g

surface coverage

3.4 μmol/m2

impurities

<10 ppm metals

matrix

silica gel, high purity, spherical base material, fully porous particle

matrix active group

C8 (octyl) phase

particle size

5 μm

pore size

180 Å

operating pH range

2-8

application(s)

food and beverages

separation technique

reversed phase

Application

Discovery® C8 HPLC column has been used in the separation of fluoroquinolone antibiotics in tablets using reversed-phase high-performance liquid chromatography (RP-HPLC).

Features and Benefits

Características de la Discovery® C8:
• Selectividad y retención clásica C18
• Excelente forma del pico
• Estable, separaciones CL/EM (LC/MS) sin sangrado
• Similar selectividad que la C18, con menor retención hidrófoba.

Legal Information

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany


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G L Bundy et al.
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The gorgonian coral Pseudoplexaura porosa contains a lipoxygenase capable of converting exogenous arachidonic acid into (8R)-8-hydroperoxy-5,9,11,14-eicosatetraenoic acid. The (8R)- (or 8-L-) configuration in this product, opposite to that observed in previously reported 8-lipoxygenase products, was determined unambiguously by comparison of
M Q Zhang et al.
Die Pharmazie, 46(10), 687-700 (1991-10-01)
The rapid growth in the quinolone research changed the whole face of the previous SAR concepts. So far structural modifications at all positions of the quinolone nucleus except the 4-oxo group have successfully lead to the discovery of potent antimicrobial