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About This Item
Empirical Formula (Hill Notation):
C73H118ClN4O9P
CAS Number:
Molecular Weight:
1262.17
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810335C-1mg), pkg of 5 × 1 mL (810335C-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
concentration
1 mg/mL (810335C-1mg), 1 mg/mL (810335C-5mg)
lipid type
fluorescent lipids
shipped in
dry ice
storage temp.
−20°C
Application
18:1 Cy5 PE or 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(Cyanine 5), chloroform has been used:
- as a standard for the estimation of absolute density of Cy5 labeled Trx-His6-NCav-CT on supported lipid bilayers (SLB)
- in annexin-coated vesicle production
- to label vesicle types in order to optically distinguish them from other vesicles and to initiate biochemical reactions in a cell-mimetic compartment
Biochem/physiol Actions
Fluorescent labelled lipids are generally useful in cell biology and biophysical studies. Cellular events involving lipids such as lipid domain generation, disaggregation and re-organization can be studied with fluorescent lipids. They are also useful in analyzing the physical properties of lipid bilayers.
Packaging
5 mL Amber Glass Screw Cap Vial (810335C-1mg)
5 mL Amber Glass Screw Cap Vial (810335C-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
target_organs
Central nervous system, Liver,Kidney
Storage Class
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
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Xiandeng Wu et al.
Molecular cell, 73(5), 971-984 (2019-01-22)
Both the timing and kinetics of neurotransmitter release depend on the positioning of clustered Ca2+ channels in active zones to docked synaptic vesicles on presynaptic plasma membranes. However, how active zones form is not known. Here, we show that RIM
Guido Bolognesi et al.
Nature communications, 9(1), 1882-1882 (2018-05-16)
Constructing higher-order vesicle assemblies has discipline-spanning potential from responsive soft-matter materials to artificial cell networks in synthetic biology. This potential is ultimately derived from the ability to compartmentalise and order chemical species in space. To unlock such applications, spatial organisation
Margrethe A Boyd et al.
Biophysical journal, 115(7), 1307-1315 (2018-09-17)
Cells dynamically regulate their membrane surface area during a variety of processes critical to their survival. Recent studies with model membranes have pointed to a general mechanism for surface area regulation under tension in which cell membranes unfold or take