161527
Sodium hydrosulfide hydrate
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Linear Formula:
NaSH·xH2O
CAS Number:
Molecular Weight:
56.06 (anhydrous basis)
NACRES:
NA.55
PubChem Substance ID:
UNSPSC Code:
12352302
MDL number:
Form:
chips, flakes
InChI
1S/Na.H2O.H2S/h;2*1H2/q+1;;/p-1
SMILES string
[Na]S.[H]O[H]
InChI key
ZNKXTIAQRUWLRL-UHFFFAOYSA-M
form
chips, flakes
concentration
≥60% (by Na2S2O3, titration)
mp
52-54 °C (lit.)
Quality Level
Related Categories
General description
Sodium hydrosulfide hydrate is a hydrated inorganic salt of sodium. It participates in the synthesis of (E)-2-cyano-2-(thiazolidin-2-ylidene)ethanethioamide.
Application
It may be used as a sulfur nucleophile to induce the C-S bond formation in α,β-dichloro vinyl ketones to form 5- to 8-membered cyclic thioethers.
Sodium hydrosulfide hydrate may be used in the synthesis of following:
- benzothiazole
- 4-methoxybenzothioamide
- 2-(4-methoxyphenyl)imidazoline
- 7-chloro-4′-methoxythioflavone
signalword
Danger
hcodes
Storage Class
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
flash_point_f
194.0 °F - closed cup
flash_point_c
90 °C - closed cup
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1B
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Mehdi Bakavoli et al.
Molecules (Basel, Switzerland), 14(12), 4849-4857 (2009-12-25)
Cyclocondensation of 2-[bis(methylthio)methylene]malononitrile (1) and cysteamine (2) afforded 2-(thiazolidin-2-ylidene)malononitrile (3). This compound on treatment with NaSH gave the corresponding thioamide derivative 4a in a regioselective manner on the basis of its single crystal X-ray diffraction analysis. Reaction of this compound
Bruna M Santos et al.
Acta physiologica (Oxford, England), 228(3), e13373-e13373 (2019-09-05)
Whereas some patients have important changes in body core temperature (Tb) during systemic inflammation, others maintain a normal Tb, which is intrinsically associated to immune paralysis. One classical model to study immune paralysis is the use of repeated administration of
Synthesis of Benzothiazoles through Copper-Catalyzed One-Pot Three-Component Reactions with Use of Sodium Hydrosulfide as a Sulfur Surrogate.
Park N, et al.
European Journal of Organic Chemistry, 10, 1984-1993 (2012)
Min Sun et al.
European journal of medicinal chemistry, 45(6), 2299-2306 (2010-02-26)
Two series of novel diaryl ureas have been designed and synthesized, with their in vitro antitumor effect screened on human non-small cell lung cancer (NSCLC) cell line A549 and human breast cancer cell line MDA-MB-231. Some target compounds demonstrated significant
Practical and Versatile Synthesis of Thioflavones from 2-Bromobenzoyl Chlorides.
Lee JI and Choi JS.
J. Korean Chem. Soc., 59(3) (2015)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service