S8875
Sodium bicarbonate
ReagentPlus®, ≥99.5%, powder
Synonym(s):
Sodium hydrogen carbonate
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About This Item
Linear Formula:
NaHCO3
CAS Number:
Molecular Weight:
84.01
UNSPSC Code:
12352302
NACRES:
NA.21
PubChem Substance ID:
EC Number:
205-633-8
Beilstein/REAXYS Number:
4153970
MDL number:
eCl@ss:
38020213
Assay:
≥99.5%
Form:
powder
agency
suitable for EPA 300
Quality Level
product line
ReagentPlus®
assay
≥99.5%
form
powder
pKa (25 °C)
(1) 6.37, (2) 10.25 (carbonic acid)
density
2.16 g/mL at 25 °C (lit.)
SMILES string
[Na+].OC([O-])=O
InChI
1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1
InChI key
UIIMBOGNXHQVGW-UHFFFAOYSA-M
General description
Sodium bicarbonate is commonly known as baking soda. It serves as a source of carbon dioxide and is used to prepare a variety of sodium salts. It is also an important pH-regulating agent.
Application
Sodium bicarbonate can be used as a catalyst:
- To synthesize nitriles from the corresponding aldehydes and hydroxylamine hydrochloride in the presence of sodium sulfate as a co-catalyst.
- To prepare coumarin derivatives via intramolecular Wittig reaction of substituted 2-formylphenyl 2-bromoacetates.
- In the acetylation of primary alcohols and phenols by reacting with acetic anhydride.
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
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Shay P McGuinness et al.
Critical care medicine, 41(7), 1599-1607 (2013-05-21)
Cardiac surgery-associated acute kidney injury occurs in up to 50% of patients and is associated with increased mortality and morbidity. This study aimed to discover if perioperative urinary alkalinization with sodium bicarbonate infusion reduces the prevalence of cardiac surgery-associated acute
Somjot S Brar et al.
Clinical journal of the American Society of Nephrology : CJASN, 4(10), 1584-1592 (2009-08-29)
Infusion of sodium bicarbonate has been suggested as a preventative strategy but reports are conflicting on its efficacy. The aim of this study was to assess the effectiveness of hydration with sodium bicarbonate for the prevention of contrast-induced acute kidney
Sophia Zoungas et al.
Annals of internal medicine, 151(9), 631-638 (2009-11-04)
Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN). To determine the effect of sodium bicarbonate on the risk for CIN. MEDLINE, PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials from 1950 to