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Merck

N1627

4-Nitrophenyl β-D-glucuronide

≥98% (TLC)

Synonym(s):

4-Nitrophenyl β-D-glucuronide, 4-Nitrophenyl-β-D-glucopyranosiduronic acid, PNPG

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About This Item

Empirical Formula (Hill Notation):
C12H13NO9
CAS Number:
10344-94-2
Molecular Weight:
315.23
UNSPSC Code:
12352200
NACRES:
NA.52
PubChem Substance ID:
24897507
EC Number:
233-753-0
Beilstein/REAXYS Number:
1438576
MDL number:
MFCD00036210

Key Documents

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InChI key

QSUILVWOWLUOEU-GOVZDWNOSA-N

InChI

1S/C12H13NO9/c14-7-8(15)10(11(17)18)22-12(9(7)16)21-6-3-1-5(2-4-6)13(19)20/h1-4,7-10,12,14-16H,(H,17,18)/t7-,8-,9+,10-,12+/m0/s1

SMILES string

O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2ccc(cc2)[N+]([O-])=O

grade

Molecular Biology

assay

≥98% (TLC)

form

powder

solubility

H2O: soluble 100 mg/mL, clear

storage temp.

−20°C

Quality Level

200

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Application

4-Nitrophenyl β-D-glucuronide has been used as substrate in acetate buffer to measure β-glucuronidase.

General description

Chromogenic substrate for β-glucuronidase (GUS) gene detection.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000430784
0000430783
0000430783
0000430784
0000349435

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Analysis of Fluorescent Compounds in Urine by Liquid Chromatography
T. Hanaia & J. Huberta
Journal of Liquid Chromatography, 7, 1627-1642 (1984)
A tool for monitoring Trichoderma harzianum: II. The use of a GUS transformant for ecological studies in the rhizosphere
Green Helge and Jensen D Funck
Phytopathology, 85(11), 1436-1440 (1995)
E S Piruzian et al.
Molecular genetics and genomics : MGG, 266(5), 778-786 (2002-01-26)
The coding region of the licB gene from Clostridium thermocellum was truncated at the 3' end. The modified lichenase encoded by the construct (LicBM2) retained the most important properties of the enzyme - its high activity and thermostability. LicBM2 consists
beta-N-Cyanoethyl acyl hydrazide derivatives: A new class of beta-glucuronidase inhibitors
Khan KM, et al.
Chemical & Pharmaceutical Bulletin, 50(11), 1443-1446 (2002)
C Y Ng et al.
The Journal of pharmacology and experimental therapeutics, 295(2), 830-835 (2000-10-25)
Congestive heart failure has been shown to affect oxidative drug metabolism, however, there has been little study of its effects on drug conjugation. Using the isolated perfused livers from rats with right ventricular failure (RVF) due to pulmonary artery constriction
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