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ST1574 Anti-GRN Rabbit pAb

ST1574
  
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Replacement Information

Tabulka spec. kláve

Host
Rb
Description
Overview

This product has been discontinued.





Recognizes the ~60 kDa GRN protein in mouse testes tissue.
Catalogue NumberST1574
Brand Family Calbiochem®
SynonymsAnti-Granulin
Application Data
Detecion of mouse GRN by immunoblotting. Sample: Whole tissue extract from mouse testes. Primary antibody: Anti-GRN Rabbit pAb (Cat. No. ST1574) (1-5 µg/ml). Detection: chemiluminescence.
References
Product Information
FormLiquid
FormulationIn PBS, pH 7.2.
Negative control293T Cells
Positive controlMouse testes tissue
PreservativeNone
Applications
Key Applications Immunoblotting (Western Blotting)
Application NotesImmunoblotting (1-5 µg/ml)
Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
Biological Information
ImmunogenFull-length, human GRN (aa 1-593)
ImmunogenHuman
HostRabbit
IsotypeIgG
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Regulatory Review
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
ST1574 0

Documentation

Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision08-November-2010 RFH
SynonymsAnti-Granulin
ApplicationImmunoblotting (1-5 µg/ml)
Application Data
Detecion of mouse GRN by immunoblotting. Sample: Whole tissue extract from mouse testes. Primary antibody: Anti-GRN Rabbit pAb (Cat. No. ST1574) (1-5 µg/ml). Detection: chemiluminescence.
DescriptionPurified rabbit polyclonal antibody. Recognizes the ~60 kDa GRN protein.
BackgroundGranulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.
HostRabbit
Immunogen speciesHuman
ImmunogenFull-length, human GRN (aa 1-593)
IsotypeIgG
Specieshuman, mouse
Positive controlMouse testes tissue
Negative control293T Cells
FormLiquid
FormulationIn PBS, pH 7.2.
PreservativeNone
CommentsVariables associated with assay conditions will dictate the proper working dilution.
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Regulatory Review