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ST1041 Anti-RKIP Rabbit pAb

Anti-RKIP Rabbit pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Raf Kinase Inhibitory Protein

ST1041
  
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Přehled

Replacement Information

Tabulka spec. kláve

Host
Rb
Description
Overview

This product has been discontinued.





Recognizes the ~23 kDa raf kinase inhibitory protein (RKIP) in H19-7 cells.
Catalogue NumberST1041
Brand Family Calbiochem®
SynonymsAnti-Raf Kinase Inhibitory Protein
Application Data
Detection of rat, mouse and human RKIP by immunoblotting. Samples: whole cell lysate from rat cells (lane 1), human cells (lane 2), and mouse cells (lane 3). Primary antibody: Anti-RKIP Rabbit pAb (Cat. No. ST1041) (1:1000). Detection: chemiluminescence.
References
ReferencesCorbit, K.C et al. 2003. J. Biol. Chem. 278,13061.
Nishizuka, Y. 1992. Science 258, 607.
Product Information
FormLiquid
FormulationUndiluted serum.
Positive controlH19-7 cells
PreservativeNone
Applications
Key Applications Immunoblotting (Western Blotting)
Immunocytochemistry
Application NotesImmunoblotting (1:2000-1:5000)
Immunocytochemistry (1:500-1:2000)
Application CommentsAntibody should be titrated for optimal results in individual systems.
Biological Information
Immunogenfull-length, recombinant rat RKIP fused to GST
ImmunogenRat
HostRabbit
IsotypeIgG
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
ST1041 0

Documentation

Anti-RKIP Rabbit pAb Certificates of Analysis

TitleLot Number
ST1041

References

Přehled odkazů
Corbit, K.C et al. 2003. J. Biol. Chem. 278,13061.
Nishizuka, Y. 1992. Science 258, 607.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision18-October-2007 RFH
SynonymsAnti-Raf Kinase Inhibitory Protein
ApplicationImmunoblotting (1:2000-1:5000)
Immunocytochemistry (1:500-1:2000)
Application Data
Detection of rat, mouse and human RKIP by immunoblotting. Samples: whole cell lysate from rat cells (lane 1), human cells (lane 2), and mouse cells (lane 3). Primary antibody: Anti-RKIP Rabbit pAb (Cat. No. ST1041) (1:1000). Detection: chemiluminescence.
DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes the ~23 kDa raf kinase inhibitory protein (RKIP).
BackgroundThe PKC family of serine/threonine kinases plays a key role in physiological processes such as growth, death, differentiation, and transformation. It has been shown that one means by which PKCs activate Raf-1 signaling to ERK involves the loss of inhibition by RKIP. Although PKCs have been well established as activators of MAP kinases, their targets in this pathway are still unknown. The mechanism of PKC-mediated Raf/MAP kinase activation is of major importance since several components of the MAP kinase pathway are mutated in human cancers.
HostRabbit
Immunogen speciesRat
Immunogenfull-length, recombinant rat RKIP fused to GST
IsotypeIgG
Specieshuman, monkey, mouse, rat
Positive controlH19-7 cells
FormLiquid
FormulationUndiluted serum.
PreservativeNone
CommentsAntibody should be titrated for optimal results in individual systems.
Storage Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Standard Handling
ReferencesCorbit, K.C et al. 2003. J. Biol. Chem. 278,13061.
Nishizuka, Y. 1992. Science 258, 607.