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SCT076 BioTracker Red Hydrogen Sulphide Live Cell Dye

Live cell imaging probe for hydrogen sulphide, a gaseous signaling molecule. Exhibits red fluorescence in presence of H2S.

SCT076
1 mg  
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Description
Catalogue NumberSCT076
DescriptionBioTracker Red Hydrogen Sulphide Live Cell Dye
OverviewHydrogen silfide (H2S) has emerged as an important gaseous signaling molecule and important physiological mediator in living organisms. The endogenous H2S is mainly produced in mitochondria or cytosol by enzymatic reactions, where it regulates energy production in mitochondria under stressful conditions. In addition, H2S appears to be involved in various physiological processes, such as suppression of oxidative stress, modulation of neurotransmission, calcium homeostasis, and long-term potentiation. Abnornal concentrations of H2S have been correlated with CNS diseases such as Down syndrome, Alzheimer's disease, and other diseases of mental deficiency.

BioTracker Blue Hydrogen sulfide live cell dye (SCT075) and BioTracker Red Hydrogen sulfide live cell dye (SCT076) are selenosulfides
tethered to gem-dimethyl esters, which act as excellent framework for H2S probe development. SCT075 and SCT076 were tested with HeLa cells and HEK293 cells. When stimulated with Na2S, these cells produced H2S, which was detected using these probes.

Spectral Properties
Excitation: 561 nm
Emission: 587 nm (Red)

References:
Suarez S.I., et al. Selenosulfides Tethered to Gem-Dimethyl Esters: A Robust and Highly Versatile Framework for H2S Probe Development. Chem. Eur. J. 2019, 25, 15736-15740.
Alternate Names
  • Live cell imaging probe
References
Product Information
Detection methodFluorescence
PresentationLyophilized
Applications
ApplicationLive cell imaging probe for hydrogen sulphide, a gaseous signaling molecule. Exhibits red fluorescence in presence of H2S.
Key Applications
  • Cell Based Assays
Application NotesLive cell fluorescent imaging
Biological Information
Molecular Weight493.43
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssurancePurity: ≥ 97% confirmed by HNMR, LC-MS and HPLC and elemental analysis
Molar Mass: 442.39 g/mol
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore BioTracker Red Hydrogen Sulphide Live Cell Dye at -20°C, desiccate and protect from light
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.
Packaging Information
Material Size1 mg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
SCT076 04061842297528