04-294
Anti-phosho-erbB2/Her2 (Tyr1112) Antibody, clone 19G5
clone 19G5, Upstate®, from mouse
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
19G5, monoclonal
Species reactivity:
canine, rat, mouse, human
Application:
ELISA, WB
Citations:
4
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
19G5, monoclonal
species reactivity
canine, rat, mouse, human
manufacturer/tradename
Upstate®
technique(s)
ELISA: suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pTyr1112)
Gene Information
human ... ERBB2(2064)
mouse ... Erbb2(13866)
General description
185 kDa
Immunogen
KLH-conjugated synthetic peptide encompassing the surrounding amino acids of Tyr1112 in human erbB2/Her2
Application
Detect phosho-erbB2/Her2 (Tyr1112) using this Anti-phosho-erbB2/Her2 (Tyr1112) Antibody, clone 19G5 validated for use in ELISA & WB.
Biochem/physiol Actions
Recognizes phosphorylated domain of erbB2/Her2 on Tyrosine 1112
Physical form
Format: Purified
Analysis Note
Control
Includes EGF treated SKOV-3 lysate as a positive control
Includes EGF treated SKOV-3 lysate as a positive control
Routinely evaluated by immunoblot.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
10 - Combustible liquids
Certificates of Analysis (COA)
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L N Klapper et al.
Cancer research, 60(13), 3384-3388 (2000-07-26)
Overexpression of HER-2/ErbB-2, a homologue of the epidermal growth factor receptor, is associated with poor prognosis, and an ErbB-2-specific antibody is therapeutic when administered to patients with metastatic breast cancer. To understand the mechanism underlying immunotherapy, we concentrated on antibody-
Leonie W Wahjudi et al.
International journal of cancer, 148(6), 1438-1451 (2020-09-20)
DNA sequencing and RNA sequencing are increasingly applied in precision oncology, where molecular tumor boards evaluate the actionability of genetic events in individual tumors to guide targeted treatment. To work toward an additional level of patient characterization, we assessed the
Erin-Mai F Lim et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(9), E1707-E1716 (2017-02-01)
AlphaB-crystallin (αBC) is a small heat shock protein that is constitutively expressed by peripheral nervous system (PNS) axons and Schwann cells. To determine what role this crystallin plays after peripheral nerve damage, we found that loss of αBC impaired remyelination
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 04-294 | 04053252367526 |