U4125
Uridine 5′-(trihydrogen diphosphate) sodium salt from Saccharomyces cerevisiae
95-100%
Synonym(s):
UDP sodium salt, Uridine 5′-(trihydrogen pyrophosphate) sodium salt
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C9H14N2O12P2 · xNa+
CAS Number:
Molecular Weight:
404.16 (free acid basis)
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay:
95-100%
Quality level:
Quality Level
assay
95-100%
solubility
H2O: soluble 100 mg/mL, clear, colorless to very faintly yellow
storage temp.
−20°C
SMILES string
[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])([O-])=O)N2C=CC(=O)NC2=O
InChI
1S/C9H14N2O12P2.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3
InChI key
GFASEGWJDXDCKZ-UHFFFAOYSA-K
Gene Information
Application
UDP has been used as a purinergic agonist to study its effects on absorptive cationic flux in cochlear outer sulcus cells (OSC) and vestibular transitional cells (VTC). UDP has also been used for nucleoside diphosphatase (NDPase) activity assays in rabbit retinae.
Biochem/physiol Actions
P2Y receptor agonist.
Features and Benefits
This compound is featured on the P2 Receptors: P2Y G-Protein Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Preparation Note
Uridine 5′-(trihydrogen diphosphate) sodium or UDP sodium salt is soluble in water at 100 mg/ml and yields a clear, colorless to very faint yellow solution.
signalword
Warning
hcodes
Hazard Classifications
STOT SE 2
target_organs
Eyes,Central nervous system
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
J Schnitzer
The Journal of comparative neurology, 282(2), 249-263 (1989-04-08)
Enzyme-histochemical methods for thiamine pyrophosphatase (TPPase) and nucleoside diphosphatase (NDPase) were applied to wholemounted rabbit retinae to demonstrate the shape and distribution of microglial cells in early postnatal and adult animals. At birth, microglial cells were already present in the
J H Lee et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 21(23), 9168-9174 (2001-11-22)
Cochlear outer sulcus cells (OSC) and vestibular transitional cells (VTC) are part of the parasensory epithelium in the inner ear and are located in homologous positions between the sensory hair cells and the cation secretory epithelial cells in the cochlea
Markie O Muoboghare et al.
British journal of pharmacology, 176(16), 2894-2904 (2019-05-23)
There is a lack of potent, selective antagonists at most subtypes of P2Y receptor. The aims of this study were to characterise the pharmacological properties of the proposed P2Y2 receptor antagonist, AR-C118925XX, and then to use it to determine the