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About This Item
Linear Formula:
CF3(CF2)7Br
CAS Number:
Molecular Weight:
498.96
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
207-028-4
Beilstein/REAXYS Number:
2016022
MDL number:
Assay:
99%
Form:
liquid
InChI key
WTWWXOGTJWMJHI-UHFFFAOYSA-N
InChI
1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26
SMILES string
FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br
assay
99%
form
liquid
Quality Level
bp
142 °C (lit.)
density
1.93 g/mL at 25 °C (lit.)
functional group
bromo, fluoro
General description
1-Bromoheptadecafluorooctane (perfluorooctyl bromide) is a perfluorocarbon. Poly(ethylene glycol)ylated polyester nanocapsules of perfluorooctyl bromide were surface-decorated with a RGD (arginine-glycine-aspartic acid) peptide, were used for tumor imaging. Nanocapsules of perfluorooctyl bromide have been developed as dual contrast agent for ultrasonography and Magnetic Resonance Imaging (MRI).
Application
1-Bromoheptadecafluorooctane (perfluorooctyl bromide) can be used as contrast agent in the vascular system for fluorine-19 magnetic resonance imaging or as synthetic oxygen carrier. It was also employed as oxygen carrier in the emulsions used as blood substitutes.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Sabah Servaes et al.
Pediatric radiology, 39(4), 393-395 (2009-02-04)
Partial liquid ventilation therapy utilizing perfluorocarbons has been used for patients with severe respiratory distress. Perfluorocarbons such as perflubron have been demonstrated to clear from the lungs shortly after therapy. We present a 13-year-old boy with residual perflubron in his
Journal of Fluorine Chemistry, 114, 119-126 (2002)
Allison E McDonald et al.
Biochimica et biophysica acta, 1807(8), 954-967 (2010-11-09)
Oxygenic photosynthesis depends on a highly conserved electron transport system, which must be particularly dynamic in its response to environmental and physiological changes, in order to avoid an excess of excitation energy and subsequent oxidative damage. Apart from cyclic electron
Sun-Joo Lee et al.
The journal of physical chemistry. B, 114(31), 10086-10096 (2010-08-06)
Perfluorocarbon-based nanoemulsion particles have arisen as promising platforms for the cellular delivery of imaging and therapeutic agents to specific targets. However, current knowledge of the agent delivery mechanism is limited to qualitative and phenomenological models. Lack of detail at the
Mitsuhiro Isaka et al.
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 14(6), 363-368 (2009-01-10)
Perfluoro-octyl bromide (PFOB), one of the perfluorochemical oxygen transporters, improved postischemic cardiac dysfunctions. Also norepinephrine (NE) is one of the important inducible factors on reperfusion arrhythmias (ventricular fibrillation [VF]). We used these methods to evaluate the relationship between PFOB emulsion
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