4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride

Name: 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride
Brand: ALDRICH

≥97.0% (calc. on dry substance, AT), for peptide synthesis

Synonym(s):

DMTMM, MMTM

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All Photos(1)

About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₇ClN₄O₃

CAS Number:

3945-69-5

Molecular Weight:

276.72

NACRES:

NA.22

PubChem Substance ID:

57652501

UNSPSC Code:

12352005

MDL number:

MFCD03613550

Beilstein/REAXYS Number:

8026872

Product Name

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride, 95% (HPLC)

InChI

1S/C10H17N4O3.ClH/c1-14(4-6-17-7-5-14)8-11-9(15-2)13-10(12-8)16-3;/h4-7H2,1-3H3;1H/q+1;/p-1

SMILES string

[Cl-].COc1nc(OC)nc(n1)[N+]2(C)CCOCC2

InChI key

BMTZEAOGFDXDAD-UHFFFAOYSA-M

assay

95% (HPLC)

form

powder

reaction suitability

reaction type: Coupling Reactions

impurities

≤17 wt. % water

application(s)

peptide synthesis

functional group

ether

storage temp.

−20°C

Quality Level

100

Related Categories

Amino Acids, Resins & Reagents for Peptide Synthesis

Building Blocks, Resins, and Coupling Reagents for GLP-1 Synthesis

Application

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride can be used as a condensing agent for the following transformations:

Condensation of carboxylic acids and amines to the corresponding amides in tetrahydrofuran.
Esterification of carboxylic acids with alcohols to the corresponding esters.
Conversion of carboxylic acids to the corresponding Weinreb amides in protic solvents.

Reagent for activating carboxylic acids in solution and solid phase peptide synthesis; superior or comparable to the most popular coupling reagents

pictograms

GHS05,GHS07

signalword

Danger

hcodes

H302,H314

pcodes

P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

198.5 °F - closed cup

flash_point_c

92.5 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Synthesis and characterization of 4-(4, 6-dimethoxy-1, 3, 5-triazin-2-yl)-4-methylmorpholinium chloride.

Kunishima M

Tetrahedron Letters, 40(29), 5327-5330 (1999)

M. Kunishima et al.

Tetrahedron Letters, 40, 5327-5327 (1999)

Inverse Electron-Demand Diels-Alder Methylcellulose Hydrogels Enable the Co-delivery of Chondroitinase ABC and Neural Progenitor Cells.

Vianney Delplace et al.

Biomacromolecules, 21(6), 2421-2431 (2020-04-11)

A hydrogel that can deliver both proteins and cells enables the local microenvironment of transplanted cells to be manipulated with a single injection. Toward this goal, we designed a hydrogel suitable for the co-delivery of neural stem cells and chondroitinase

Esterification of carboxylic acids with alcohols by 4-(4, 6-dimethoxy-1, 3, 5-triazin-2-yl)-4-methyl-morpholinium chloride (DMTMM).