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About This Item
Linear Formula:
BrC6H4COCH2Br
CAS Number:
Molecular Weight:
277.94
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
202-783-6
Beilstein/REAXYS Number:
607604
MDL number:
Product Name
2,4′-Dibromoacetophenone, >98%
InChI key
FKJSFKCZZIXQIP-UHFFFAOYSA-N
InChI
1S/C8H6Br2O/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2
SMILES string
BrCC(=O)c1ccc(Br)cc1
assay
>98%
form
crystals
mp
108-110 °C (lit.)
Quality Level
Gene Information
human ... PLA2G2A(5320)
rat ... Pla2g2a(29692)
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Related Categories
Application
Undergoes condensation reactions with aldehydes in the presence of SnCl2 or SmI3 to afford α,β-unsaturated ketones. Also useful in the esterification of carboxylic acids.
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Tetrahedron Letters, 34, 4547-4547 (1993)
Synthetic Communications, 23, 271-271 (1993)
Tetrahedron, 49, 9735-9735 (1993)
Rodrigo G Stábeli et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 142(3-4), 371-381 (2006-01-31)
MjTX-II, a myotoxic phospholipase A(2) (PLA(2)) homologue from Bothrops moojeni venom, was functionally and structurally characterized. The MjTX-II characterization included: (i) functional characterization (antitumoral, antimicrobial and antiparasitic effects); (ii) effects of structural modifications by 4-bromophenacyl bromide (BPB), cyanogen bromide (CNBr)
Youngjin Park et al.
Archives of insect biochemistry and physiology, 60(3), 105-115 (2005-10-20)
We report on a secretory phospholipase A2 (sPLA2) associated with membrane-enriched fractions prepared from hemocytes of the tobacco hornworms, Manduca sexta. Virtually no PLA2 activity was detected in serum of immunologically naive or bacterially challenged hornworms. PLA2 activity was detected
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