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Merck

R1757

D-(−)-Ribose

98%

Synonym(s):

D-Ribose

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About This Item

Empirical Formula (Hill Notation):
C5H10O5
CAS Number:
Molecular Weight:
150.13
UNSPSC Code:
12352201
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-059-4
Beilstein/REAXYS Number:
1723081
MDL number:
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Product Name

D-(−)-Ribose, 98%

InChI key

PYMYPHUHKUWMLA-LMVFSUKVSA-N

InChI

1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1

SMILES string

OC[C@@H](O)[C@@H](O)[C@@H](O)C([H])=O

assay

98%

optical activity

[α]20/D −19.7°, c = 4 in H2O

mp

88-92 °C (lit.)

Quality Level

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Raman K Sharma et al.
Bioorganic & medicinal chemistry, 20(23), 6821-6830 (2012-10-27)
A series of peracetylated O-aryl α,β-d-ribofuranosides have been synthesized and an efficient biocatalytic methodology has been developed for the separation of their anomers which was otherwise almost impossible by column chromatographic or other techniques. The incubation of 2,3,5-tri-O-acetyl-1-O-aryl-α,β-d-ribofuranoside with Lipozyme®
P De Wulf et al.
Applied microbiology and biotechnology, 48(2), 141-148 (1997-08-01)
The production of D-ribose by fermentation has received much attention lately, possibly because of the use of this pentose to synthesize antiviral and anticancer drugs. This review briefly outlines the methods that have been used to synthesize D-ribose since it
Paul O Hassa et al.
Frontiers in bioscience : a journal and virtual library, 13, 3046-3082 (2007-11-06)
Poly-ADP-ribose metabolism plays a mayor role in a wide range of biological processes, such as maintenance of genomic stability, transcriptional regulation, energy metabolism and cell death. Poly-ADP-ribose polymerases (PARPs) are an ancient family of enzymes, as evidenced by the poly-ADP-ribosylating
Anders Virtanen et al.
Critical reviews in biochemistry and molecular biology, 48(2), 192-209 (2013-03-19)
Deadenylation of eukaryotic mRNA is a mechanism critical for mRNA function by influencing mRNA turnover and efficiency of protein synthesis. Here, we review poly(A)-specific ribonuclease (PARN), which is one of the biochemically best characterized deadenylases. PARN is unique among the
Carine Baraguey et al.
Organic & biomolecular chemistry, 11(16), 2638-2647 (2013-03-05)
The pivaloyloxymethyl (PivOM) group is a biolabile 2'-O-ribose protection that is under development in a prodrug-based approach for siRNA applications. Besides an expected cellular uptake, nucleic acid sequences carrying PivOM showed also increased nuclease resistance and, in most cases, an

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