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Merck

880400P

Avanti

16:0 PEG350 PE

Avanti Research - A Croda Brand

Synonym(s):

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] (ammonium salt)

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About This Item

CAS Number:
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

16:0 PEG350 PE, Avanti Research - A Croda Brand 880400P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 200 mg (880400P-200mg), pkg of 1 × 25 mg (880400P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 880400P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]

InChI

1S/C53H104NO17P.H3N/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-51(55)68-48-50(71-52(56)31-29-27-25-23-21-19-17-15-13-11-9-7-5-2)49-70-72(58,59)69-33-32-54-53(57)67-47-46-66-45-44-65-43-42-64-41-40-63-39-38-62-37-36-61-35-34-60-3;/h50H,4-49H2,1-3H3,(H,54,57

InChI key

AEGGEICNCATQIE-VDKVIGKMSA-N

General description

16:0 PEG350 PE is a polyethylene glycol (PEG) conjugated phospholipid. It is a biopolymer with a molecular weight of 1075.4 Da.

Application

16:0 PEG350 PE is suitable for use in the preparation of Pdots and to differentiate based on shell′s composition. It might also be used in membrane preparation to study water dynamics.

Biochem/physiol Actions

Polyethylene glycol (PEG) conjugated phospholipids are useful in liposome formulation for maintaining their stereochemistry. They also serve as drug carriers. PEGylated lipids aid in the formation of mixed micelles at high concentration.

Packaging

20 mL Clear Glass Screw Cap Vial (880400P-200mg)
5 mL Clear Glass Sealed Ampule (880400P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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Storage Class

11 - Combustible Solids

wgk

WGK 3



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Eduardo M Clop et al.
The journal of physical chemistry. B, 118(23), 6150-6158 (2014-05-09)
The present work was aimed at studying the molecular dynamics at different levels of model membranes having a simulated glycoclix, with focus on the molecular crowding conditions at the lipid-water interfacial region. Thus, binary mixtures of dipalmitoylphosphatidylcholine (dpPC) and a
Pdots nanoparticles load photosensitizers and enhance efficiently their photodynamic effect by FRET
Haimov E, et al.
Royal Society of Chemistry Advances, 5(24), 18482-18491 (2015)
Maria C Sandström et al.
Langmuir : the ACS journal of surfaces and colloids, 23(8), 4192-4198 (2007-03-09)
Polyethylene glycol (PEG)-conjugated lipids are commonly employed for steric stabilization of liposomes. When added in high concentrations PEG-lipids induce formation of mixed micelles, and depending on the lipid composition of the sample, these may adapt either a discoidal or a