Skip to Content
Merck

8.05740

2-Mercaptoethanol

for synthesis

Synonym(s):

Thioethylene glycol, Thioglycol, β-Mercaptoethanol, 2-Hydroxyethylmercaptan, BME, Thioethylene glycol

Sign In to View Organizational & Contract Pricing.

Select a Size

All Photos(2)

About This Item

Linear Formula:
HSCH2CH2OH
CAS Number:
60-24-2
Molecular Weight:
78.13
UNSPSC Code:
12352104
NACRES:
NA.22
EC Index Number:
200-464-6
MDL number:
MFCD00004890
Beilstein/REAXYS Number:
773648

Product Name

2-Mercaptoethanol, for synthesis

InChI key

DGVVWUTYPXICAM-UHFFFAOYSA-N

SMILES string

OCCS

InChI

1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2

vapor density

2.69 (vs air)

vapor pressure

1 mmHg ( 20 °C)

assay

≥99% (GC)

form

liquid

autoignition temp.

295 °C

potency

98-162 mg/kg LD50, oral (Rat)
112-224 mg/kg LD50, skin (Rabbit)

expl. lim.

18 %

reaction suitability

reagent type: reductant

concentration

14.3 M (pure liquid)

refractive index

n20/D 1.500 (lit.)

pH

4.5-6 (20 °C, 500 g/L in H2O)

bp

157 °C (lit.)

mp

<-50 °C

transition temp

flash point 70.5 °C

density

1.114 g/mL at 25 °C (lit.)

storage temp.

2-30°C

Quality Level

200

Related Categories

Application

BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1A - STOT RE 2 Oral

Storage Class

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

165.2 °F - closed cup

flash_point_c

74 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Georg Michlits et al.
Nature methods, 17(7), 708-716 (2020-06-10)
CRISPR-Cas9 screens have emerged as a transformative approach to systematically probe gene functions. The quality and success of these screens depends on the frequencies of loss-of-function alleles, particularly in negative-selection screens widely applied for probing essential genes. Using optimized screening

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service