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Merck

B0070000

Bacampicillin hydrochloride

European Pharmacopoeia (EP) Reference Standard

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About This Item

Empirical Formula (Hill Notation):
C21H27N3O7S · HCl
CAS Number:
37661-08-8
Molecular Weight:
501.98
MDL number:
MFCD11215256
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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Product Name

Bacampicillin hydrochloride, European Pharmacopoeia (EP) Reference Standard

SMILES string

S1[C@H]2N([C@H](C1(C)C)C(=O)OC(OC(=O)OCC)C)C(=O)[C@H]2NC(=O)[C@H](N)c3ccccc3.[Cl-].[H+]

InChI

1S/C21H27N3O7S.ClH/c1-5-29-20(28)31-11(2)30-19(27)15-21(3,4)32-18-14(17(26)24(15)18)23-16(25)13(22)12-9-7-6-8-10-12;/h6-11,13-15,18H,5,22H2,1-4H3,(H,23,25);1H/t11?,13-,14-,15+,18-;/m1./s1

InChI key

IWVTXAGTHUECPN-ANBBSHPLSA-N

grade

pharmaceutical primary standard

API family

bacampicillin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Bacampicillin hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

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Y Akimoto et al.
General pharmacology, 24(4), 895-898 (1993-07-01)
1. Ampicillin concentrations in cyst wall (wall) and cyst fluid (fluid) of radicular cyst and serum following a single oral administration of bacampicillin (equivalent to 500 mg of ampicillin) were measured by a paper disk method. 2. The mean peak
J Laurent et al.
Alimentary pharmacology & therapeutics, 15(11), 1787-1793 (2001-10-31)
Helicobacter pylori eradication rates in France after therapy with omeprazole, amoxicillin and clarithromycin are among the lowest in Europe. This study evaluated alternative eradication regimens. Helicobacter pylori-positive patients (n=323) with non-ulcer dyspepsia were randomized to receive one of four 1-week
H Saka et al.
Kokyu to junkan. Respiration & circulation, 40(11), 1105-1108 (1992-11-01)
To evaluate the effect of bacampicillin hydrochloride on fever following fiberoptic bronchoscopy and bronchography, we conducted multi-institutional randomized study. In bronchographic examinations, the rise of body temperatures in the bacampicillin group (0.82 +/- 0.13 degrees C: mean +/- SE) was
M Bogataj et al.
Journal of microencapsulation, 8(3), 401-406 (1991-07-01)
Eudragit E microspheres containing bacampicillin hydrochloride were prepared by solvent evaporation and solvent extraction methods. Three different systems of solvents were used: methyl acetate, acetone and methanol/liquid paraffin. The success of the procedures depended mostly on the lipophilicity of the
Y Akimoto et al.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 50(1), 11-13 (1992-01-01)
Ampicillin concentrations in human serum and radicular granulomas of 42 patients were determined after a single oral dose of bacampicillin (equivalent to 500 mg of ampicillin). Although wide variations were found among both serum and radicular granuloma ampicillin concentrations, measurable
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