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About This Item
Empirical Formula (Hill Notation):
C20H8Br4O5
CAS Number:
Molecular Weight:
647.89
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
239-138-3
MDL number:
Colour Index Number:
45380:2
Product Name
Eosin Y, Dye content ~99 %
form
powder
Quality Level
composition
Dye content, ~99%
color
light red to red/pink
solubility
ethanol: 1 mg/mL
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
Oc1c(Br)cc2c(Oc3c(Br)c(O)c(Br)cc3C24OC(=O)c5ccccc45)c1Br
InChI
1S/C20H8Br4O5/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20/h1-6,25-26H
InChI key
DBZJJPROPLPMSN-UHFFFAOYSA-N
Application
Eosin Y has been used as a stain:
- to determine the location of the brain sections
- for staining of fixed liver tissue
- for histological examination of brain sections from the dorsal hippocampus
Biochem/physiol Actions
Eosin Y is a xanthene dye and is used for the differential staining of connective tissue and cytoplasm. In histopathology, it is applied as a counterstain after hematoxylin and before methylene blue. It is also used as a background stain, thereby giving contrast to the nuclear stains.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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The effects of simvastatin on hippocampal caspase-3 and Bcl-2 expression following kainate-induced seizures in rats.
Sun J, et al.
International Journal of Molecular Medicine, 30, 739-739 (2012)
Antonello Mai et al.
Journal of medicinal chemistry, 51(7), 2279-2290 (2008-03-20)
A number of new compounds bearing two ortho-bromo- and ortho, ortho-dibromophenol moieties linked through a saturated/unsaturated, linear/(poly)cyclic spacer (compounds 1- 9) were prepared as simplified analogues of AMI-5 (eosin), a recently reported inhibitor of both protein arginine and histone lysine
Inactivation of NF-kappaB p50 leads to insulin sensitization in liver through post-translational inhibition of p70S6K.
Gao Z, et al.
The Journal of Biological Chemistry, 284, 18368-18368 (2009)