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Merck

T7875

Thiourea

≥99.0%, ReagentPlus®

Synonym(s):

Sulfourea, Thiocarbamide

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About This Item

Linear Formula:
NH2CSNH2
CAS Number:
62-56-6
Molecular Weight:
76.12
NACRES:
NA.21
PubChem Substance ID:
57654702
UNSPSC Code:
12352100
EC Number:
200-543-5
MDL number:
MFCD00008067
Beilstein/REAXYS Number:
605327

Key Documents

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Product Name

Thiourea, ReagentPlus®, ≥99.0%

InChI key

UMGDCJDMYOKAJW-UHFFFAOYSA-N

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

SMILES string

NC(N)=S

product line

ReagentPlus®

assay

≥99.0%

mp

170-176 °C (lit.)

functional group

amine
thiourea

Quality Level

200

Gene Information

mouse ... Ephx2(13850)

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Application

Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins
Thiourea has been used:
  • as a component in ice cold sample buffer for protein analysis
  • in intracellular extraction buffer for the extraction of soluble intracellular proteins
  • as a component of electrophoresis buffer

Biochem/physiol Actions

Thiourea is a free radical scavenger of the peroxide radical. It was shown to inhibit lipid peroxidation and ultraviolet (UV)-induced crosslinking of collagen. Bud dormancy in plants can be inhibited by thiourea, which is used as a growth stimulator. It is also known to be used in the treatment of hyperthyroidism.

General description

Thiourea is an analogue of urea, containing sulphur.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

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Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ9539
MKCZ9538
MKCX9029
MKCW7592
MKCT3367

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Feline hypertrophic cardiomyopathy associated with the p. A31P Mutation in cMyBP-C is caused by production of mutated cMyBP-C with reduced binding to actin
Godiksen MTN, et al.
Open Journal of Veterinary Medicine, 3(02), 95-95 (2013)
Synergistic effects of glucose and ultraviolet irradiation on the physical properties of collagen
Ohan MP, et al.
Journal of Biomedical Materials Research, 60(3), 384-391 (2002)
Extraction of Intracellular and Cell Wall Proteins from Leaves and Roots of Harsh Hakea
Shane MW and Plaxton WC
Journal of Experimental Botany (2014)
Protocol: Optimised methodology for isolation of nuclei from leaves of species in the Solanaceae and Rosaceae families
Sikorskaite S, et al.
Plant methods, 9(1), 31-31 (2013)
Mechanism of the reduction of methylene blue by thiourea in aqueous acidic medium
Osunlaja AA
International Journal of ChemTech Research, 4(2), 609-617 (2012)
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