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About This Item
Linear Formula:
[(CH3)2CH]2C6H3OH
CAS Number:
Molecular Weight:
178.27
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI
1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3
SMILES string
CC(C)c1cccc(C(C)C)c1O
InChI key
OLBCVFGFOZPWHH-UHFFFAOYSA-N
grade
pharmaceutical primary standard
vapor pressure
5.6 mmHg ( 100 °C)
API family
propofol
manufacturer/tradename
EDQM
refractive index
n20/D 1.514 (lit.)
bp
256 °C/764 mmHg (lit.)
mp
18 °C (lit.)
density
0.962 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Gene Information
Related Categories
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Propofol for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
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Philippe E Dubois et al.
European journal of anaesthesiology, 31(8), 404-410 (2013-07-26)
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Eran A Mukamel et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(3), 839-845 (2014-01-17)
Rhythmic oscillations shape cortical dynamics during active behavior, sleep, and general anesthesia. Cross-frequency phase-amplitude coupling is a prominent feature of cortical oscillations, but its role in organizing conscious and unconscious brain states is poorly understood. Using high-density EEG and intracranial
Cynthia Ménard et al.
Radiology, 274(1), 181-191 (2014-09-10)
To determine if the integration of diagnostic magnetic resonance (MR) imaging and MR-guided biopsy would improve target delineation for focal salvage therapy in men with prostate cancer. Between September 2008 and March 2011, 30 men with biochemical failure after radiation
Muhammad Suleman Khan et al.
Basic & clinical pharmacology & toxicology, 115(6), 565-570 (2014-06-04)
A variety of techniques have been developed to monitor the depth of anaesthesia. Propofol's pharmacokinetics and response vary greatly, which might be explained by genetic polymorphisms. We investigated the impact of genetic variations on dosage, anaesthetic depth and recovery after
Ryu Komatsu et al.
Anesthesia and analgesia, 117(6), 1329-1337 (2013-11-22)
Because etomidate impairs adrenal function and blunts the cortisol release associated with surgical stimulus, we hypothesized that patients induced with etomidate suffer greater mortality and morbidity than comparable patients induced with propofol. We evaluated the electronic records of 31,148 ASA
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