Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer⁸³¹) antibody produced in rabbit

AMPA is a transmembrane receptor for glutamate that regulates synapsis in the central nervous system. It is composed of 4 types of subunits, GluR1, 2, 3, 4.

GluR1 subunits of AMPA receptors are membrane proteins that regulate synaptic plasticity of the central nervous system. This receptor has also been implicated in spatial memory retention. Phosphorylation of serine 831 in GluR1 subunit of the AMPA receptor modulates long-term potentiation in neuronal synapses. Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer⁸³¹) antibody is specific for the GluR1 subunit (phosphorylated on serine 831) of the AMPA receptor in rats and humans.

The GluR1 sequence is conserved among species and has partial homology to VGLUT2.

synthetic phosphopeptide corresponding to a region near serine 831 of rat glutamate receptor subunit GluR1.

Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer⁸³¹) antibody is suitable for use in direct ELISA, immunohistochemistry, immunoblot and immunoprecipitation. The antibody may also be used for western blot (1:1,000 using rat hippocampal homogenate).

Solution in 10 mM HEPES buffer, pH 7.5, containing 150 mM NaCl, 100 μg/ml BSA and 50% glycerol.

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