Key Documents

View All Documentation

C2901

Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated

Name: Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated
Brand: SIGMA

≥95% (HPLC), powder

Synonym(s):

CCK-8, non-sulfated

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₄₉H₆₂N₁₀O₁₃S₂

CAS Number:

25679-24-7

Molecular Weight:

1063.21

NACRES:

NA.32

PubChem Substance ID:

24892546

UNSPSC Code:

12352202

MDL number:

MFCD00076488

Assay:

≥95% (HPLC)

Form:

powder

Quality level:

200

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Level

200

assay

≥95% (HPLC)

form

powder

UniProt accession no.

P06307

storage temp.

−20°C

SMILES string

CSCCC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(N)CC(O)=O)C(=O)NCC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NC(CCSC)C(=O)NC(CC(O)=O)C(=O)NC(Cc4ccccc4)C(N)=O

InChI

1S/C49H62N10O13S2/c1-73-18-16-34(55-47(70)37(21-28-12-14-30(60)15-13-28)58-44(67)32(50)23-41(62)63)45(68)53-26-40(61)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(71)56-35(17-19-74-2)46(69)59-39(24-42(64)65)49(72)57-36(43(51)66)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52,60H,16-24,26,50H2,1-2H3,(H2,51,66)(H,53,68)(H,54,61)(H,55,70)(H,56,71)(H,57,72)(H,58,67)(H,59,69)(H,62,63)(H,64,65)

InChI key

OIXQINQYMGNCII-UHFFFAOYSA-N

Gene Information

human ... CCK(885)

Description

Application

Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated has been used in the specificity testing against gastrin and pepsinogen I proteins.

Biochem/physiol Actions

Biologically inactive form of CCK-8; CCK_B/gastrin receptor agonist that has no activity at the CCK_A receptor.

Cholecystokinin (CCK) is a 115 amino acid preprohormone and a neurotransmitter. It exists in many isoforms. The octapeptide of CCK (CCK-8S) is the most abundant form. CCK is mapped to human chromosome 3p22.1. CCK interacts with receptors of the gastrointestinal tract and nervous system. Polymorphisms in the CCK is implicated in hallucinations in patients with Parkinson′s disease. CCK plays a key role in the activation of the calcineurin-regulated nuclear factor of activated T-cells (NFATs).

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

0000524135

0000514341

0000260807

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Genetic substrates of psychosis in patients with Parkinson's disease: a critical review.

Lenka A, et al.

Journal of the Neurological Sciences, 364(5), 33-41 (2016)

Identification of tyrosine 189 and asparagine 358 of the cholecystokinin 2 receptor in direct interaction with the crucial C-terminal amide of cholecystokinin by molecular modeling, site-directed mutagenesis, and structure/affinity studies.

Gales C, et al.

Molecular Pharmacology, 63(5), 973-982 (2003)

Cholecystokinin activates pancreatic calcineurin-NFAT signaling in vitro and in vivo.

Gurda GT, et al.

Molecular Biology of the Cell, 19(1), 198-206 (2008)

View All Related Papers