D2631
Dihexadecyl phosphate
Synonym(s):
DHP, Dicetyl phosphate
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About This Item
Linear Formula:
[CH3(CH2)15O]2P(O)OH
CAS Number:
Molecular Weight:
546.85
UNSPSC Code:
51191904
NACRES:
NA.25
PubChem Substance ID:
EC Number:
218-594-7
Beilstein/REAXYS Number:
1717117
MDL number:
InChI key
RNPXCFINMKSQPQ-UHFFFAOYSA-N
InChI
1S/C32H67O4P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-35-37(33,34)36-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-32H2,1-2H3,(H,33,34)
SMILES string
OP(OCCCCCCCCCCCCCCCC)(OCCCCCCCCCCCCCCCC)=O
description
anionic
form
powder
mol wt
546.85 g/mol
technique(s)
DNA extraction: suitable
mp
74-75 °C (lit.)
lipid type
phospholipids
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Dihexadecyl phosphate (DHP) is a negatively charged lipid that is used for the formation of model membranes.
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Ba Hieu Tran et al.
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S-propargyl-cysteine (SPRC; alternatively known as ZYZ-802) is a novel modulator of endogenous tissue H2S concentrations with known cardioprotective and anti-inflammatory effects. However, its rapid metabolism and excretion have limited its clinical application. To overcome these issues, we have developed some
Hamdy Abdelkader et al.
Journal of pharmaceutical sciences, 100(5), 1833-1846 (2011-01-20)
This study aimed at preparing and evaluating Span 60-based niosomes for ocular delivery of naltrexone hydrochloride (NTX). Selected charged lipids [dicetyl phosphate (DCP) and stearyl amine (STA)] and surfactants [poly-24-oxyethylene cholesteryl ether (C24) and sodium cholate (CH)] were investigated as
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Journal of controlled release : official journal of the Controlled Release Society, 266, 301-309 (2017-10-11)
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Abbas Pardakhty et al.
International journal of pharmaceutics, 328(2), 130-141 (2006-09-26)
In this study, niosomes of polyoxyethylene alkyl ethers (Brij) were prepared for encapsulation of insulin by film hydration method. Without cholesterol, brij 35 and brij 58 did not form niosomes, apparently because of relatively large polar head groups in comparison
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European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 129, 257-266 (2018-06-15)
The nose-to-brain delivery of ghrelin loaded in liposomes is a promising approach for the management of cachexia. It could limit the plasmatic degradation of ghrelin and provide direct access to the brain, where ghrelin's specific receptors are located. Anionic liposomes
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