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About This Item
Linear Formula:
C11H13N3O5
CAS Number:
Molecular Weight:
285.25
NACRES:
NA.83
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
230-748-5
MDL number:
Beilstein/REAXYS Number:
2818758
Product Name
L-Glutamic acid γ-(4-nitroanilide), γ-glutamyl transpeptidase substrate
InChI key
WMZTYIRRBCGARG-VIFPVBQESA-N
InChI
1S/C11H13N3O5/c12-9(11(16)17)5-6-10(15)13-7-1-3-8(4-2-7)14(18)19/h1-4,9H,5-6,12H2,(H,13,15)(H,16,17)/t9-/m0/s1
SMILES string
N[C@@H](CCC(=O)Nc1ccc(cc1)[N+]([O-])=O)C(O)=O
assay
≥98% (HPLC)
form
powder
solubility
formic acid: 50 mg/mL, clear to slightly hazy
storage temp.
2-8°C
Quality Level
Related Categories
General description
Substrate for γ-glutamyl transpeptidase
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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L Dvoráková et al.
General physiology and biophysics, 15(5), 403-413 (1996-10-01)
The initial rate kinetics of rat kidney gamma-glutamyl transpeptidase were measured using L-gamma-glutamyl-p-nitroanilide and glycyl-glycine as the donor and the acceptor substrate, respectively. Experimental data were fitted with the initial rate equation, and the obtained results indicated that: (1) Michaelis
Gololobov MYu et al.
The Biochemical journal, 304 ( Pt 3), 869-876 (1994-12-15)
Acyl-transfer catalysed by gamma-glutamyltranspeptidase from bovine kidney was studied using gamma-L- and gamma-D-Glu-p-nitroanilide as the donor and GlyGly as the acceptor. The transfer of the gamma-Glu group to GlyGly was shown to be accompanied by transfer of the gamma-Glu group
S Finney et al.
The Biochemical journal, 324 ( Pt 3), 797-805 (1997-06-15)
1. Crude salivary gland extract of the giant Amazon leech, Haementeria ghilianii, contains an inhibitor of plasma factor XIIIa. 2. The inhibitory agent was purified to homogeneity by anion-exchange, cation-exchange, gel-filtration and reverse-phase chromatography to yield a single band on
Y Carrion et al.
Biochemical pharmacology, 45(12), 2527-2535 (1993-06-22)
The effect of thyroid hormone administration on liver glutathione (GSH) content and gamma-glutamyltransferase activity in the isolated perfused liver was studied for a period of 1-7 days in fed rats following a single dose of 0.1 mg 3,5,3'-L-triiodothyronine (T3)/kg. T3
I P Baskova et al.
Biokhimiia (Moscow, Russia), 55(4), 674-679 (1990-04-01)
The molecular mass of destabilase isolated from the medicinae leech Hirudo medicinalis was found to be equal to 12.3 kDa. A kinetic analysis of the sole presently known synthetic substrate, L-gamma-Glu-pNA, showed that the enzyme is relatively stable to heating
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