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About This Item
CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-931-5
MDL number:
Product Name
γ-Glutamyltranspeptidase from porcine kidney, Type IV, 2.0-6.0 units/mg solid
Quality Level
type
Type IV
form
powder
specific activity
2.0-6.0 units/mg solid
storage temp.
−20°C
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Analysis Note
Crude
Application
γ-Glutamyltranspeptidase is used in the food industry to improve the umami taste of soy sauce.
Biochem/physiol Actions
γ- Glutamyltranspeptidase cleaves theγ-glutamyl amide bond from glutathione and its S-conjugates to remove glutamate.
Other Notes
One unit will liberate 1.0 μmole of p-nitroaniline from L-γ-glutamyl-p-nitroanilide per min at pH 8.5 at 25°C.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Improving the umami taste of soy sauce by the addition of bacterial γ-glutamyltranspeptidase as a glutaminase to the fermentation mixture
K. Kijima & H. Suzuki
Enzyme and Microbial Technology, 41, 80-84 (2007)
S S Tate et al.
Molecular and cellular biochemistry, 39, 357-368 (1981-09-25)
gamma-Glutamyl transpeptidase catalyzes transfer of the gamma-glutamyl moiety of glutathione to amino acids, dipeptides, and to glutathione itself; the enzyme also catalyzes the hydrolysis of glutathione to glutamate and cysteinyl-glycine. This review deals with the tissue distribution and localization of
γ-Glutamyl transferase and its role as a biomarker of systemic malignancies other than hepatocellular carcinomas.
Shailendra Kapoor
European journal of gastroenterology & hepatology, 25(3), 387-387 (2013-01-26)
Stephanie Wickham et al.
The Biochemical journal, 450(3), 547-557 (2013-01-11)
GGT (γ-glutamyl transpeptidase) is an essential enzyme for maintaining cysteine homoeostasis, leukotriene synthesis, metabolism of glutathione conjugates and catabolism of extracellular glutathione. Overexpression of GGT has been implicated in many pathologies, and clinical inhibitors of GGT are under development for
Yasuteru Urano
Gan to kagaku ryoho. Cancer & chemotherapy, 40(3), 299-303 (2013-03-20)
Fluorescence imaging is one of the most powerful techniques currently available for continuous observation of dynamic intracellular processes in living cells. Suitable fluorescence probes are naturally of critical importance for fluorescence imaging, and we have succeeded to construct several versatile
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