I1774
Iturin A from Bacillus subtilis
≥95% (HPLC), suitable for microbiological culture
Product Name
Iturin A from Bacillus subtilis, ≥95% (HPLC)
biological source
Bacillus subtilis
assay
≥95% (HPLC)
form
powder
technique(s)
microbiological culture: suitable
color
white to yellow
solubility
ethanol: soluble 9.80-10.20 mg/mL
antibiotic activity spectrum
fungi
mode of action
cell membrane | interferes
storage temp.
2-8°C
Quality Level
Application
Iturin A was used in the study of Bacillomycin D (an iturin with antifungal activity against Aspergillus flavus).
Biochem/physiol Actions
IturinA exhibits strong antifungal activity against pathogenic yeast and fungi. It interacts with the cytoplasmic membrane of the target cell forming ion conducting pores. Its mode of action could be attributed to its interaction with sterols and phospholipids. The compound causes the release of exo-vesicles from human erythrocytes.
Other Notes
A family of lipopeptides characterized by a heptapeptide cyclized with a C13-C17 β-amino fatty acid. Composed mainly of C14-C15 β-amino acids.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Jun Yuan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(26), 2746-2750 (2011-08-30)
Iturin A, a powerful antifungal surfactant, is a kind of bacterial lipopeptide produced by Bacillus strains. This study addresses the use of an aqueous two-phase system (ATPS) using ethanol/ammonium sulfate to extract iturin A from Bacillus amyloliquefaciens NJN-6 fermentation broth
Chie Niisawa et al.
The Journal of general and applied microbiology, 54(3), 149-158 (2008-07-26)
A composting product of marine animal resources has been used as a fertilizer and a soil conditioner in Japan. This compost was produced by a repeated fed-batch fermentation system with three successive aerobic bioreactors. Composting temperature reached about 75 degrees
Minakshi Grover et al.
Current microbiology, 60(2), 99-106 (2009-09-25)
Bacillus subtilis strain RP24, isolated from rhizoplane of field grown pigeon pea, exhibited in vitro antagonism against a wide range of phytopathogenic fungi. An attempt was made to partially purify and characterize the diffusible antifungal metabolite/s produced by the strain
Katarzyna Czaczyk et al.
Polish journal of microbiology, 57(4), 313-319 (2008-01-01)
Cell surface hydrophobicity (CSH) is recognised as a important factor in microbial adhesion to solid surfaces. Growth conditions have been found to determine the synthesis of extracellular molecules by microorganisms. It has major consequences in modification of bacterial surface properties
R V Velho et al.
Letters in applied microbiology, 52(6), 660-666 (2011-04-20)
To investigate the expression of sboA and ituD genes among strains of Bacillus spp. at different pH and temperature. Different Bacillus strains from the Amazon basin and Bacillus subtilis ATCC 19659 were investigated for the production of subtilosin A and
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