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I4625

Inosine 5′-monophosphate disodium salt hydrate

from yeast, Grade III, ≥98% (HPLC)

Synonym(s):

5′-IMP-Na2, 5′-Inosinic acid disodium salt hydrate, I-5′-P, IMP, Inosinic Acid

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About This Item

Empirical Formula (Hill Notation):
C10H11N4O8PNa2 · xH2O
CAS Number:
352195-40-5
Molecular Weight:
392.17 (anhydrous basis)
NACRES:
NA.51
PubChem Substance ID:
24896058
UNSPSC Code:
41106305
MDL number:
MFCD00150372
Assay:
≥98% (HPLC)
Biological source:
yeast
Form:
powder
Solubility:
water: 50 mg/mL, clear, colorless
Storage temp.:
2-8°C
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Quality Level

200

biological source

yeast

type

Grade III

assay

≥98% (HPLC)

form

powder

solubility

water: 50 mg/mL, clear, colorless

storage temp.

2-8°C

SMILES string

[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])([O-])=O)n2cnc3C(=O)NC=Nc23

InChI

1S/C10H13N4O8P.2Na.H2O/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1

InChI key

KQCIGEIXDXQSGM-MSQVLRTGSA-L

Application

Inosine 5′-monophosphate (IMP) is used as a substrate to study the distribution, specificity and kinetics of inosine-5′-monophosphate dehydrogenase (IMPDH).
Inosine 5′-monophosphate disodium salt hydrate has been used:
  • as a 5′-ribonucleotide tastant compound in taste-detection threshold tests in chicks
  • for standard curve generation in high-performance liquid chromatography (HPLC) to quantify IMP from prawn tail tissue samples
  • as a component of McCoy′s 5A complete medium for Plasmodium vivax culture

Biochem/physiol Actions

Inosine 5′-monophosphate (IMP) is a dietary nucleotide that is synthesized from adenosine monophosphate (AMP) in eukaryotes. It is a food additive and is essential for intestinal health and immunity.
Inosine monophosphate, or inosinic acid, is the ribonucleotide of hypoxanthine and the first nucleotide formed during purine synthesis.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN9712
BCCM7625
BCCM1011
BCCL2520
BCCH0944

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Shira L Cheled-Shoval et al.
Poultry science, 96(7), 2206-2218 (2017-03-25)
The sense of taste has a key role in nutrient sensing and food intake in animals. A standardized and simple method for determination of tastant-detection thresholds is required for chemosensory research in poultry. We established a 24-h, 2-alternative, forced-choice solution-consumption
Effect of salt treatments on survival and consumer acceptability of freshwater prawn, Macrobranchium rosenbergii
Ciaramella MA, et al.
Aquaculture (Amsterdam, Netherlands), 428 (428)
G Q Zhang et al.
Poultry science, 87(7), 1364-1369 (2008-06-26)
An experiment was conducted to evaluate the effects of dietary inosinic acid (inosine 5'-monophosphate, IMP) on carcass characteristics, meat quality, and deposition of IMP in Arbor Acres broilers. A total of two hundred forty 1-d-old male Arbor Acres broilers were
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