M7523
Anti-Myosin (Skeletal) antibody produced in rabbit
whole antiserum
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IHC (p)
Citations:
31
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
whole antiserum
antibody product type
primary antibodies
clone
polyclonal
contains
15 mM sodium azide
species reactivity
human
enhanced validation
independent
Learn more about Antibody Enhanced Validation
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:20 using human or animal skeletal muscle, indirect immunofluorescence: 1:20 using human or animal sletetal muscle
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... MYH13(8735), MYH3(4621), MYL1(4632)
General description
Myosin is a 480,000 dalton protein containing two identical heavy chains (200,000 daltons each) and four light chains (15,000-26,000 daltons). Myosin molecules consist of two major regions: tails (rods) and heads; they aggregate into filaments through the tail region. Multiple forms of myosin heavy chains exist for each muscle type; skeletal, cardiac, smooth and non-muscle isomyosin forms exist in different types of skeletal muscle, depending on the physiological function of the muscle.
Immunogen
whole myosin (heavy and light chains) from human skeletal muscle.
Application
Anti-Myosin (Skeletal) antibody produced in rabbit has been used in:
- immunohistochemistry
- immunostaining
- western blotting
- immunofluorescence
- immunolocalization
- immunocytochemistry
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)
Western Blotting (1 paper)
Immunocytochemistry (1 paper)
Western Blotting (1 paper)
Biochem/physiol Actions
Specifically labels the A bands of human and animal skeletal muscle. Does not stain human smooth muscle tissue.
Analysis Note
The antiserum has been treated to remove lipoproteins.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
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Related Content
Instructions
Małgorzata Zimowska et al.
International journal of molecular sciences, 21(9) (2020-05-13)
Skeletal muscle regeneration depends on the satellite cells, which, in response to injury, activate, proliferate, and reconstruct damaged tissue. However, under certain conditions, such as large injuries or myopathies, these cells might not sufficiently support repair. Thus, other cell populations
Human fallopian tube: a new source of multipotent adult mesenchymal stem cells discarded in surgical procedures
Jazedje T, et al.
Journal of Translational Medicine, 7(1), 1-10 (2009)
Fatima Bianca A Dessouki et al.
Pharmaceuticals (Basel, Switzerland), 13(12) (2020-12-16)
Doxorubicin (Dox)-induced muscle toxicity (DIMT) is a common occurrence in cancer patients; however, the cause of its development and progression is not established. We tested whether inflammation-triggered cell death, "pyroptosis" plays a role in DIMT. We also examined the potential