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P7943

L-α-Phosphatidylethanolamine from egg yolk

Type III, ≥97% (TLC), lyophilized powder

Synonym(s):

1,2-Diacyl-sn-glycero-3-phosphoethanolamine, L-α-Cephalin

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About This Item

CAS Number:
39382-08-6
UNSPSC Code:
51191904
NACRES:
NA.25
EC Number:
254-438-4
MDL number:
MFCD00146357
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biological source

egg yolk

Quality Level

200

type

Type III

assay

≥97% (TLC)

form

lyophilized powder

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

[P](=O)(OC[C@H](OC(=O)CCCCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCC)(OCCN)O

InChI

1S/C40H80NO8P/c1-3-5-7-9-11-13-15-17-18-19-20-21-23-25-27-29-31-33-40(43)49-38(37-48-50(44,45)47-35-34-41)36-46-39(42)32-30-28-26-24-22-16-14-12-10-8-6-4-2/h38H,3-37,41H2,1-2H3,(H,44,45)/t38-/m1/s1

InChI key

NJGIRBISCGPRPF-KXQOOQHDSA-N

General description

L-α-Phosphatidylethanolamine from egg yolk has high unsaturated fatty acid content and elicits radical-scavenging activity. L-α-Phosphatidylethanolamine (PE) is a membrane phospholipid and is interconverted to phosphotidylserine in the presence of phosphatidylserine synthase 2. PE is essential for maintaining the structural integrity of membranes. It is the second most abundant phospholipid in animals, plants and yeast and the major lipid in bacteria. It is synthesized in mitochondria in mammals.

Application

L-α-Phosphatidylethanolamine from egg yolk has been used:
  • as a component of lipid mixture for the synthesis of giant unilamellar vesicles (GUVs)
  • in ceramide phosphoethanolamine (CPE) synthase assay using crude sphingomyelin synthase-related protein from Hela cells
  • for the standard curve generation for the quantification of lipids in plantaris muscle homogenates from mice

Packaging

Packaged under Argon.

Disclaimer

Purity when prepared is 97-99%. Solutions exposed to room temperature can decompose 0.3-0.5% per day.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000508820
0000508820
0000495800
0000495800
0000463833

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Scolopendin 2, a cationic antimicrobial peptide from centipede, and its membrane-active mechanism
Lee H, et al.
Biochimica et Biophysica Acta - Biomembranes, 1848(2), 634-642 (2015)
Egg Yolk Phosphatidylethanolamine: Extraction Optimization, Antioxidative Activity, and Molecular Structure Profiling
Sun N, et al.
Journal of Food Science (2019)
Tingbo Ding et al.
Journal of lipid research, 56(3), 537-545 (2015-01-22)
Sphingomyelin synthase-related protein (SMSr) synthesizes the sphingomyelin analog ceramide phosphoethanolamine (CPE) in cells. Previous cell studies indicated that SMSr is involved in ceramide homeostasis and is crucial for cell function. To further examine SMSr function in vivo, we generated Smsr
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