RAB0278
Rat IL-1 β ELISA Kit
for cell and tissue lysates
Synonym(s):
Il-1 beta, Interleukin-1 beta
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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
rat ... Il1b(24494)
Input:
sample type cell lysate
sample type tissue lysate
sample type tissue lysate
Species reactivity:
rat
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
rat
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, capture ELISA: suitable
input
sample type cell lysate
sample type tissue lysate
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/mL
standard curve range: 68.59-50000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
rat ... Il1b(24494)
General description
The Rat IL-1 β ELSA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Rat IL-1β cell lysate and tissue lysate.
Immunogen
Recombinant Rat IL-1 β
Application
For research use only. Not for use in diagnostic procedures
Rat IL-1 Β ELISA Kit has been used to measure IL-1 Β levels .
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Rat IL-1 Β ELISA Kit has been used to measure IL-1 Β levels .
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Pro-inflammatory cytokine IL-1 Β (IL1B), which is highly expressed on Β-adrenoreceptor in obese adipose tissues, is implicated in induction of uncoupling protein 1 (UCP1) expression via extracellular signal-regulated kinase (ERK) activation in adipocytes. Macrophage autophagy inhibits the production of inflammasome-dependent IL-1Β and thereby it plays a vital role in reducing acute toxin-induced liver injury and death. In rats, IL-1Β enhanced neurogenesis and plasticity of carotid bodies (CB) by triggering ERK1/2 activation. IL-1Β plays a vital role in alteration of glomerular hemodynamics via stimulating the production of prostaglandin E2 (PGE2) in the mesangial cells.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
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Kit Components Also Available Separately
Product No.
Description
SDS & Pricing
pcodes
signalword
Warning
hcodes
Hazard Classifications
Met. Corr. 1
Storage Class
10 - Combustible liquids
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Instructions
Interleukin-1? promotes the neurogenesis of carotid bodies by stimulating the activation of ERK1/2.
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