RAB0601
Human FGF1 / Fibroblast Growth Factor 1 ELISA Kit
for serum, plasma, cell culture supernatants and urine
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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... FGF1(2246)
Input:
sample type urine
sample type cell culture supernatant(s)
sample type plasma
sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type serum
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type urine
sample type cell culture supernatant(s)
sample type plasma
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 12 pg/mL
standard curve range: 16.38-4000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... FGF1(2246)
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
FGF1 (fibroblast growth factor 1) is mainly involved in cell growth, proliferation and neurogenesis. It also participates in wound healing, post-ischemic heart repair and making of collaterals after hindlimb ischemia. FGF1 functions as an angiogenic factor that participates in tissue repair, carcinogenesis and maintenance of vasculature stability.
The FGF1 ELISA kit provides for the quantitative measurement of Fibroblast Growth Factor 1 in Cell Culture Supernatants, Plasma and Serum.
General description
FGF1 (fibroblast growth factor 1) gene encodes a member of the fibroblast growth factor (FGF) family. It encodes a pro-angiogenic protein that is ubiquitously expressed. In humans, FGF1 is alternatively spliced into four forms: FGF1A (in kidney), FGF1B (in brain), FGF1-C and -D (in vascular smooth muscle cells and fibroblasts). This gene is located on human chromosome 5q31.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
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Yash Chhabra et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(5), 6412-6430 (2019-02-20)
Growth hormone (GH) has an important function as an insulin antagonist with elevated insulin sensitivity evident in humans and mice lacking a functional GH receptor (GHR). We sought the molecular basis for this sensitivity by utilizing a panel of mice
Upregulation of fibroblast growth factor 1 in the synovial membranes of patients with late stage osteoarthritis.
Li R, et al.
Genetics and molecular research : GMR, 14(3), 11191-11199 (2015)
Regulation of FGF1 gene promoter through transcription factor RFX1.
Hsu YC, et al.
The Journal of Biological Chemistry (2010)
Hongyu Guan et al.
Cell & bioscience, 8, 26-26 (2018-04-11)
Innate immunity activator (INAVA) has been shown to be elevated in lung adenocarcinoma. However, its expression pattern and function in papillary thyroid cancer (PTC) are unknown. This study aimed to identify the clinical, biological, and mechanistic impacts of INAVA on
Transgenic expression of nonclassically secreted FGF suppresses kidney repair.
Kirov A, et al.
PLoS ONE, 7(5), e36485-e36485 (2012)
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