RAB0806
Mouse IgM ELISA Kit
Synonym(s):
IgM, Immunoglobulin M
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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
species reactivity
mouse
technique(s)
ELISA: suitable
assay range
inter-assay cv: <10%
intra-assay cv: <12%
shipped in
wet ice
storage temp.
−20°C
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
General description
Immunoglobulin M (IgM) is a highly conserved antibody in vertebrates and shows early expression during the immune response. Peritoneal B cells secrete IgM and it exists as a pentamer. IgM plays a key role in engulfing the apoptotic cells. A reduction in the serum IgM levels leads to an increase in autoimmune response and a higher risk for infections. IgM displays polyreactive and autoreactive functionality. It plays a key role in tissue homeostasis by mediating the clearance of tissue-based molecules. The antibody pair provided in this kit recognizes mouse IgM.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
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Lori Broderick et al.
Nature communications, 10(1), 3644-3644 (2019-08-15)
B cell development is a highly regulated process involving multiple differentiation steps, yet many details regarding this pathway remain unknown. Sequencing of patients with B cell-restricted immunodeficiency reveals autosomal dominant mutations in TOP2B. TOP2B encodes a type II topoisomerase, an
Stefan Malafa et al.
PLoS neglected tropical diseases, 14(2), e0008034-e0008034 (2020-02-06)
Zika virus has recently spread to South- and Central America, causing congenital birth defects and neurological complications. Many people at risk are flavivirus pre-immune due to prior infections with other flaviviruses (e.g. dengue virus) or flavivirus vaccinations. Since pre-existing cross-reactive
A A R Thompson et al.
Science immunology, 2(8) (2017-04-08)
Hypoxia and bacterial infection frequently co-exist, in both acute and chronic clinical settings, and typically result in adverse clinical outcomes. To ameliorate this morbidity, we investigated the interaction between hypoxia and the host response. In the context of acute hypoxia
Simon A Reid et al.
BMC public health, 17(1), 671-671 (2017-08-24)
Zoonotic diseases such as leptospirosis occur as a result of the often complex interactions that exist at the human-animal-environment interface. The most obvious consequence of this complexity is the need for the health sector to partner with institutions in other
Lene H Harritshøj et al.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 73, 7-9 (2018-05-29)
This study was performed to determine the seroprevalence and incidence of hepatitis E virus (HEV) infection among HIV-infected women during pregnancy and after delivery in a cohort of 200 Tanzanian women. HIV-infected women participating in a study on antiretroviral therapy
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