X1126
Xylazine
≥99%, Alpha-2 adrenergic agonist
Synonym(s):
2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazine
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About This Item
Empirical Formula (Hill Notation):
C12H16N2S
CAS Number:
Molecular Weight:
220.33
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
230-902-1
MDL number:
Assay:
≥99%
Quality level:
Product Name
Xylazine, ≥99%
Quality Level
assay
≥99%
drug control
Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet
storage temp.
−20°C
SMILES string
Cc1cccc(C)c1NC2=NCCCS2
InChI
1S/C12H16N2S/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12/h3,5-6H,4,7-8H2,1-2H3,(H,13,14)
InChI key
BPICBUSOMSTKRF-UHFFFAOYSA-N
General description
Xylazine is soluble in methanol (50 mg/ml), yielding a clear, colorless solution. It is also soluble in dilute HCl acid and in chloroform. Xylazine is practically insoluble in water and in alkali solutions.
Application
Xylazine has been used to anaesthetise experimental animals.
Biochem/physiol Actions
α2-adrenoceptor agonist, sedative, muscle relaxant.
Xylazine when used along with ketamine is considered to be a potent and safe anaesthetic in experimental animal. It is known to elevate the hepatic release of glucose, which aggravates to hyperglycemia.
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signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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Product Information Sheet
MIND model for triple-negative breast cancer in syngeneic mice for quick and sequential progression analysis of lung metastasis
Ghosh A, et al.
PLoS ONE, 13(5), e0198143-e0198143 (2018)
Acute reversible cataract induced by xylazine and by ketamine-xylazine anesthesia in rats and mice
Calderone L, et al.
Experimental Eye Research, 42(4), 331-337 (1986)
Effect of xylazine on plasma glucose, glucagon and insulin concentrations in sheep
Brockman, RP
Research in Veterinary Science, 30(3), 383-384 (1981)