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Merck

05-486

Anti-FADD Antibody, clone 1F7

clone 1F7, Upstate®, from mouse

Synonym(s):

Anti-GIG3, Anti-IMD90, Anti-MORT1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-FADD Antibody, clone 1F7, clone 1F7, Upstate®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

1F7, monoclonal

species reactivity

mouse, human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG1

NCBI accession no.

NM_003824

UniProt accession no.

Q13158

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... FADD(8772)
mouse ... Fadd(14082)

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Replaces: 04-1113

Physical form

Format: Purified
PBS, pH 7.2 and 50% glycerol
Protein A chromatography

Analysis Note

Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
routinely evaluated by immunoblot on RIPA lysates from Jurkat cells

Application

Anti-FADD Antibody, clone 1F7 detects level of FADD & has been published & validated for use in WB.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

Biochem/physiol Actions

FADD

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

28kDa

Immunogen

GST-tagged full-length fusion protein corresponding to human FADD

Preparation Note

2 years at -20°C

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hayley I Muendlein et al.
Science (New York, N.Y.), 367(6484), 1379-1384 (2020-03-21)
Cell death and inflammation are interdependent host responses to infection. During pyroptotic cell death, interleukin-1β (IL-1β) release occurs through caspase-1 and caspase-11-mediated gasdermin D pore formation. In vivo, responses to lipopolysaccharide (LPS) result in IL-1β secretion. In vitro, however, murine
Suppression of TNF receptor-1 signaling in an in vitro model of epileptic tolerance.
Thompson, SJ; Ashley, MD; Stohr, S; Schindler, C; Li, M; McCarthy-Culpepper, KA; Pearson et al.
International Journal of Physiology, Pathophysiology and Pharmacology null
Death domain mutagenesis of KILLER/DR5 reveals residues critical for apoptotic signaling
McDonald, E. R., 3rd, et al
The Journal of Biological Chemistry, 276, 14939-14945 (2001)
Simon Thompson et al.
The Journal of biological chemistry, 286(22), 19331-19339 (2011-04-12)
We have previously shown that the cell death-promoting protein Bcl-2-interacting mediator of cell death (Bim) is ubiquitinated and degraded following a neuroprotection-conferring episode of brief ischemia (preconditioning). Here, we identify the E3 ligase that ubiquitinates Bim in this model, using
Eun-Young Ahn et al.
International journal of cancer, 100(4), 445-451 (2002-07-13)
Human cholangiocarcinoma is a malignancy with no effective therapy and a poor prognosis. Previously, we demonstrated that cultured human cholangiocarcinoma cell lines heterogeneously express Fas on their surface, resulting in 2 subpopulations, Fas-high and Fas-low cells. Fas-low cells are resistant
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Global Trade Item Number

SKUGTIN
05-48604053252273124

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