Skip to Content
Merck

Key Documents

View All Documentation

137666

Ethylene glycol

EMPROVE® EVOLVE

Synonym(s):

Ethylene Glycol Emprove® Evolve, 1,2-Ethanediol

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Linear Formula:
HOCH2CH2OH
CAS Number:
107-21-1
Molecular Weight:
62.07
UNSPSC Code:
12352137
Beilstein/REAXYS Number:
505945
MDL number:
MFCD00002885
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

400

agency

CIP (cleaning in place)

vapor density

2.1 (vs air)

vapor pressure

0.053 hPa ( 20 °C), 0.08 mmHg ( 20 °C)

product line

EMPROVE® EVOLVE

assay

≥99.5% (GC)

form

liquid

autoignition temp.

410 °C, 752 °F

expl. lim.

15.3 %, 3.2-15.3 %

impurities

≤0.00002% Chloride (CI), ≤0.001% Acidity (as CH3COOH)

refractive index

n20/D 1.431 (lit.)

pH

6-7.5 (20 °C, 100 g/L)

bp

195-198 °C, 197.6 °C/1013 hPa

mp

-14--10 °C, −13 °C (lit.)

transition temp

flash point 111 °C

density

1.11 g/cm3 at 20 °C, 1.113 g/mL at 25 °C (lit.)

application(s)

pharma/biopharma processes

storage temp.

2-30°C

SMILES string

OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

General description

The new Ehtylene Glycol Emprove® Evolve meets the increasing quality requirements of of the biopharma industry for cleaning and storage of protein A resin.
We offer a range of high quality critical raw materials plus the documentation and expertise to help our customers meet stringent regulatory requirements. Our SAFC® portfolio of high-quality products withstands strict quality control procedures.

Application

Ethylene Glycol EMPROVE® Evolve meets the increasing quality requirements of the biopharma industry for cleaning and storage of protein A resin in downstream processes.
This chemical is used in the downstream process for the cleaning and storage of protein A resin.

Features and Benefits

Ethylene Glycol Emprove® Evolve cleaning and storage chemical can increase the lifetime of our Eshmuno® A resin as well as other protein A resins.

Packaging

Packsizes:
  • 1376661000: 1 L
  • 1376669025: 25 L
  • 1376669950: 950 L

Other Notes

More than 100% increase in column lifetime was achieved using a mixture of 20 % Ethylene Glycol and 0.1M NaOH solution. As a comparison, using traditional 0.1M solution resulted in an 80 % drop after just 250 cycles compared to an impressive 600 cycles using Ethylene Glycol Emprove® Evolve and 0.1M NaOH solution.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Still not finding the right product?

Explore all of our products under Ethylene glycol

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - STOT RE 2 Oral

target_organs

Kidney

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

239.0 °F - open cup

flash_point_c

115 °C - open cup

pictograms

Health hazardExclamation mark
GHS08,GHS07

hcodes

H302,H373

Stay compliant with GMP using the Emprove® Program

Accelerate qualification, maintain compliance, and save time with Emprove® Dossiers.

Download Dossiers

Note: you will be brought to EmproveSuite.com. Your username and password are separate from SigmaAldrich.com and may differ.

Register for free and access Emprove® Dossiers within minutes. Upgrade your subscription plan to unlock advanced and customized content in the Emprove® Suite

Not finding what you are looking for? Visit the Emprove® Program Help page.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library