8.00592
Phthalic anhydride
for synthesis
Synonym(s):
Phthalic anhydride
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About This Item
vapor pressure
<0.01 hPa ( 20 °C)
Quality Segment
form
crystals
autoignition temp.
580 °C
potency
1530 mg/kg LD50, oral (Rat), >3160 mg/kg LD50, skin (Rabbit)
expl. lim.
1.7-10.5 % (v/v)
pH
2 (20 °C, 6 g/L in H2O)
bp
285 °C/1013 hPa
mp
131 °C
transition temp
flash point 152 °C
solubility
6 g/L (slow decomposition)
density
1.527 g/cm3 at 20 °C
bulk density
500‑700 kg/m3
storage temp.
no temp limit
SMILES string
O1C(=O)c2c(cccc2)C1=O
InChI
1S/C8H4O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h1-4H
InChI key
LGRFSURHDFAFJT-UHFFFAOYSA-N
Application
<li><strong>Antibacterial and cytotoxic activity of chitosan derivatives:</strong>Phthalic anhydride-modified chitosan derivatives exhibit significant antibacterial and cytotoxic properties, suggesting their potential application in medical and pharmaceutical products (Sousa et al., 2024).</li>
<li><strong>Heterodinuclear Polymerization Catalysts:</strong> Research identified Al(III)/K(I) polymerization catalysts that utilize phthalic anhydride for producing high-quality polyester polyols, offering advancements in polymer synthesis technology (Shellard et al., 2024).</li>
<li><strong>Advanced epoxy vitrimers:</strong> Phthalic anhydride was used in the design and synthesis of advanced epoxy vitrimers with enhanced glass transition temperatures, important for applications requiring high-performance thermoset polymers (Dai et al., 2023).</li>
<li><strong>Sustainable alkyd resins:</strong> The utilization of phthalic anhydride in the production of alkyd resins from bio-based resources represents a significant move towards more sustainable and environmentally friendly coating applications (Dizman and Cerrahoglu Ka and ccedil;akgil, 2023).</li>
</ul>
Analysis Note
Melting range (lower value): ≥ 129 °C
Melting range (upper value): ≤ 133 °C
Identity (IR): conforms
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Danger
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 1
flash_point_f
305.6 °F - DIN 51758
flash_point_c
152 °C - DIN 51758
Certificates of Analysis (COA)
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