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Merck

AB15766

Anti-Sox1 Antibody

Chemicon®, from rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
18

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, mouse, rodent, human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

NM_005986.2

UniProt accession no.

O00570

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... SOX1(6656)

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Immunogen

Synthetic peptide from human Sox1.

Application

Anti-Sox1 Antibody detects level of Sox1 & has been published & validated for use in WB, IH.
Research Sub Category
Neuronal & Glial Markers

Developmental Neuroscience
Western blot: 1:200-1:1,000 using ECL. Immunohistochemistry: 1:200-1:1,000. Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Reactivity with other species has not been confirmed.
Recognizes Sox-1, a high mobility group (HMG) transcription factor.

Physical form

Affinity purified immunoglobulin. Precipitated antibody in a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.
Format: Purified

Other Notes

Replaces: AB5768

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Catarina M Seabra et al.
Molecular autism, 11(1), 45-45 (2020-06-07)
MBD5, encoding the methyl-CpG-binding domain 5 protein, has been proposed as a necessary and sufficient driver of the 2q23.1 microdeletion syndrome. De novo missense and protein-truncating variants from exome sequencing studies have directly implicated MBD5 in the etiology of autism
Ying Pei et al.
Brain research, 1638(Pt A), 57-73 (2015-08-10)
Induced pluripotent stem cells (iPSC) and their differentiated derivatives offer a unique source of human primary cells for toxicity screens. Here, we report on the comparative cytotoxicity of 80 compounds (neurotoxicants, developmental neurotoxicants, and environmental compounds) in iPSC as well
Kiyohito Murai et al.
Nature communications, 7, 10965-10965 (2016-03-12)
Dysregulated expression of miR-219, a brain-specific microRNA, has been observed in neurodevelopmental disorders, such as schizophrenia (SCZ). However, its role in normal mammalian neural stem cells (NSCs) and in SCZ pathogenesis remains unknown. We show here that the nuclear receptor
Fabien Almairac et al.
Cancer research, 80(16), 3236-3250 (2020-05-06)
There is great interest in understanding how the cancer stem cell population may be maintained in solid tumors. Here, we show that tumor cells exhibiting stem-like properties and expression of pluripotency markers NANOG and OCT4 can arise from original differentiated
N Mellios et al.
Molecular psychiatry, 23(4), 1051-1065 (2017-04-26)
Rett syndrome (RTT) is an X-linked, neurodevelopmental disorder caused primarily by mutations in the methyl-CpG-binding protein 2 (MECP2) gene, which encodes a multifunctional epigenetic regulator with known links to a wide spectrum of neuropsychiatric disorders. Although postnatal functions of MeCP2
View All Related Papers

Global Trade Item Number

SKUGTIN
AB1576604053252506482

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