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Merck

07-2980

Diethylene glycol monoethyl ether

SAJ first grade, ≥98.0%

Synonym(s):

2-(2-Ethoxyethoxy)ethanol, CARBITOL™, Diethylene glycol ethyl ether, Ethyldiglycol

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About This Item

Linear Formula:
C2H5OCH2CH2OCH2CH2OH
CAS Number:
111-90-0
Molecular Weight:
134.17
EC Number:
203-919-7
UNSPSC Code:
12352112
PubChem Substance ID:
329748401
Beilstein/REAXYS Number:
1736441
MDL number:
MFCD00002872

Key Documents

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grade

SAJ first grade

vapor density

4.63 (vs air)

vapor pressure

0.12 mmHg ( 20 °C)

assay

≥98.0%

form

liquid

expl. lim.

1.2 %, 135 °F, 23.5 %, 182 °F

availability

available only in Japan

refractive index

n20/D 1.427 (lit.)

bp

202 °C (lit.)

density

0.999 g/mL at 25 °C (lit.)

SMILES string

CCOCCOCCO

InChI

1S/C6H14O3/c1-2-8-5-6-9-4-3-7/h7H,2-6H2,1H3

InChI key

XXJWXESWEXIICW-UHFFFAOYSA-N

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Legal Information

CARBITOL is a trademark of The Dow Chemical Company or an affiliated company of Dow

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

204.8 °F - closed cup

flash_point_c

96 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificates of Analysis (COA)

Lot/Batch Number
A1233
A6768
A6557
A3229
A7863

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Simona Mura et al.
Journal of drug targeting, 19(3), 189-196 (2010-05-08)
The aim of this work was to evaluate the ability of Transcutol (Trc) to produce elastic vesicles with soy lecithin (SL) and study the influence of the obtained vesicles on in vitro (trans)dermal delivery of minoxidil. To this purpose, so-called
Hyun-Jong Cho et al.
International journal of pharmaceutics, 423(2), 153-160 (2012-01-03)
To achieve rapid onset of action and improved bioavailability of udenafil, a microemulsion system was developed for its intranasal delivery. Phase behavior, particle size, transmission electron microscope (TEM) images, and the drug solubilization capacity of the microemulsion were investigated. A
Jeoung Hee Yoo et al.
Archives of pharmacal research, 33(3), 417-426 (2010-04-03)
Self-nanoemulsifying drug delivery system (SNEDDS) containing oil (Phosal 53 MCT), surfactant (Labrasol), and cosurfactant (Transcutol-HP or Lutrol-E400) was prepared to enhance solubility and dissolution of lutein. Ternary phase diagram of the SNEDDS was constructed to identify the self-emulsifying regions following
Bhupinder Singh et al.
Drug delivery, 18(8), 599-612 (2011-10-20)
Carvedilol, a widely prescribed cardiovascular drug for hypertension and congestive heart failure, exhibits low and variable bioavailability owing to poor absorption and extensive hepatic first-pass metabolism. The current research work, therefore, entails formulation development of liquid self-nano-emulsifying drug delivery systems
Rania M Hathout et al.
Molecular pharmaceutics, 7(4), 1266-1273 (2010-06-16)
This research determined the uptake of individual components of topically applied microemulsions into the stratum corneum (SC) and assessed their molecular effects on skin barrier function. The microemulsions comprised oleic acid, Tween20, Transcutol and water. The effects of selected formulations
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