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Merck

02671

Carbon tetrachloride

analytical standard

Synonym(s):

Tetrachloromethane

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About This Item

Empirical Formula (Hill Notation):
CCl4
CAS Number:
Molecular Weight:
153.82
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-262-8
Beilstein/REAXYS Number:
1098295
MDL number:

Product Name

Carbon tetrachloride, analytical standard

InChI key

VZGDMQKNWNREIO-UHFFFAOYSA-N

InChI

1S/CCl4/c2-1(3,4)5

SMILES string

ClC(Cl)(Cl)Cl

grade

analytical standard

vapor density

5.32 (vs air)

vapor pressure

143 mmHg ( 30 °C)
91 mmHg ( 20 °C)

assay

≥99.95% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.460 (lit.)
n20/D 1.460

bp

76-77 °C (lit.)

mp

−23 °C (lit.)

density

1.594 g/mL at 25 °C (lit.)

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

Quality Level

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Application

CCl4 may have been used as reference standard in colorimetric analysis to determine CCl4 in fatty liver sample.

Other Notes

Sales restrictions may apply

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 2 - Ozone 1 - Skin Sens. 1B - STOT RE 1 Inhalation

target_organs

Liver,Kidney

Storage Class

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Biochemical changes in carbon tetrachloride fatty liver: concentration of carbon tetrachloride in liver and blood.
RECKNAGEL RO, LITTERIA M.
The American Journal of Pathology, 36, 521-531 (1960)
Bruce D. Craig, David S. Anderson
Handbook of Corrosion Data, 257-257 (1994)
Lutz W D Weber et al.
Critical reviews in toxicology, 33(2), 105-136 (2003-04-24)
The use of many halogenated alkanes such as carbon tetrachloride (CCl4), chloroform (CHCl3) or iodoform (CHI3), has been banned or severely restricted because of their distinct toxicity. Yet CCl4 continues to provide an important service today as a model substance
Samuele De Minicis et al.
Hepatology (Baltimore, Md.), 59(5), 1738-1749 (2013-08-21)
Nonalcoholic fatty liver disease (NAFLD) may lead to hepatic fibrosis. Dietary habits affect gut microbiota composition, whereas endotoxins produced by Gram-negative bacteria stimulate hepatic fibrogenesis. However, the mechanisms of action and the potential effect of microbiota in the liver are
Bi-Sen Ding et al.
Nature, 505(7481), 97-102 (2013-11-22)
Chemical or traumatic damage to the liver is frequently associated with aberrant healing (fibrosis) that overrides liver regeneration. The mechanism by which hepatic niche cells differentially modulate regeneration and fibrosis during liver repair remains to be defined. Hepatic vascular niche

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