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Merck

31626

Bacitracin A

VETRANAL®, analytical standard, main stereoisomer ~50 %

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About This Item

Empirical Formula (Hill Notation):
C66H103N17O16S
Molecular Weight:
1422.69
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
245-115-9
NACRES:
NA.24
E Number:
E700
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Product Name

Bacitracin A, VETRANAL®, analytical standard, main stereoisomer ~50 %

SMILES string

CC[C@H](C)[C@H](N)C1=N[C@@H](CS1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)NC([C@@H](C)CC)C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc4ccccc4)NC(=O)C(NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

composition

main stereoisomer, ~50%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

Quality Level

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Application

Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Bacitracin is a polypeptide antibiotic produced by strains of Bacillus subtilis and Bacillus licheniformis. Bacitracin A is a commercially produced, major microbiologically active component of bacitracin.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)


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Walter Mancino et al.
Microorganisms, 7(12) (2019-12-08)
Specific members of the genus Bifidobacterium are among the first colonizers of the human/animal gut, where they act as important intestinal commensals associated with host health. As part of the gut microbiota, bifidobacteria may be exposed to antibiotics, used in
Mukundan Ragavan et al.
Analytical chemistry, 83(15), 6054-6059 (2011-06-10)
Hyperpolarization of nuclear spins through techniques such as dynamic nuclear polarization (DNP) can greatly increase the signal-to-noise ratio in NMR measurements, thus eliminating the need for signal averaging. This enables the study of many dynamic processes which would otherwise not
A M Neumüller et al.
European journal of biochemistry, 268(11), 3180-3189 (2001-06-08)
Bacitracin is a peptide antibiotic produced by several Bacillus licheniformis strains that is most active against other Gram-positive microorganisms, but not against the producer strain itself. Recently, heterologous expression of the bacitracin resistance mediating BcrABC transporter in Bacillus subtilis and
Quantitative high-pressure liquid chromatographic analysis of bacitracin, a polypeptide antibiotic.
Tsuji K, et al.
Journal of Chromatography A, 99(4), 597- 608 (1974)
M M Siegel et al.
Biological mass spectrometry, 23(4), 186-204 (1994-04-01)
The bacitracin antibiotic complex consists principally of bacitracin A, a peptide antibiotic containing seven amino acid residues in a ring and five amino acid residues in a blocked side chain, together with a mixture of minor components presumably related but

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