A3759
p-Aminohippuric acid sodium salt
Synonym(s):
N-(p-Aminobenzoyl)glycine
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About This Item
Linear Formula:
C9H9N2O3Na
CAS Number:
Molecular Weight:
216.17
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
202-309-8
MDL number:
assay
≥98% (TLC)
form
powder
color
white to off-white
application(s)
cell analysis
SMILES string
[Na].Nc1ccc(cc1)C(=O)NCC(O)=O
InChI
1S/C9H10N2O3.Na.H/c10-7-3-1-6(2-4-7)9(14)11-5-8(12)13;;/h1-4H,5,10H2,(H,11,14)(H,12,13);;
InChI key
IGACXVXMVJUFOL-UHFFFAOYSA-N
Biochem/physiol Actions
Para-Aminohippuric acid (PAH), OAT-1 specific, is used to help differentiate and characterized organic anion transporter (OAT) isoforms.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Product Information Sheet
M M Al-Bataineh et al.
Journal of veterinary pharmacology and therapeutics, 35(3), 209-215 (2011-06-01)
Mammary epithelial cells express a diversity of membrane transporters including members of organic cation and organic anion (OAT) transporter subfamilies. Four mammal OAT isoforms have been identified: OAT-1, OAT-2, OAT-3, and OAT-4. The pharmacological significance of OAT isoforms has been
Chiao-Shih Tseng et al.
Advances in pharmacological sciences, 2011, 204501-204501 (2011-07-09)
The characteristics of aristolochic acid nephropathy (AAN) are interstitial fibrosis and atrophy of the proximal tubules, but with no change in glomeruli. To investigate the effects of AA on renal functions and the pharmacokinetics (PKs) of p-aminohippuric acid (PAH) and
Nadiya Bakhiya et al.
Toxicology, 264(1-2), 74-79 (2009-08-01)
Aristolochic acid (AA), present in Aristolochia species, is the major causative agent in the development of severe renal failure and urothelial cancers in patients with AA nephropathy. It may also be a cause of Balkan endemic nephropathy. Epithelial cells of