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Merck

C1276

L-Cysteine hydrochloride

≥98% (TLC), suitable for UHPLC

Synonym(s):

(2R)-2-Amino-3-sulfanylpropanoic acid hydrochloride

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About This Item

Linear Formula:
HSCH2CH(NH2)COOH · HCl
CAS Number:
52-89-1
Molecular Weight:
157.62
NACRES:
NA.32
PubChem Substance ID:
24892395
UNSPSC Code:
12352209
EC Number:
200-157-7
MDL number:
MFCD00064553
Beilstein/REAXYS Number:
3560277

Product Name

L-Cysteine hydrochloride, anhydrous, ≥98% (TLC)

InChI key

IFQSXNOEEPCSLW-DKWTVANSSA-N

InChI

1S/C3H7NO2S.ClH/c4-2(1-7)3(5)6;/h2,7H,1,4H2,(H,5,6);1H/t2-;/m0./s1

SMILES string

Cl[H].N[C@@H](CS)C(O)=O

grade

anhydrous

assay

≥98% (TLC)

form

powder

technique(s)

UHPLC: suitable

color

white

mp

174.1-174.7 °C

solubility

H2O: 50 mg/mL, clear, colorless

Quality Level

200

Gene Information

human ... AMPA 1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893), GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRIN3A(116443), GRIN3B(116444), GRINA(2907)
mouse ... AMPA 1(14799), GRIA2(14800), GRIA3(53623), GRIA4(14802), GRIN1(14810), GRIN2A(14811), GRIN2B(14812), GRIN2C(14813), GRIN2D(14814), GRIN3A(242443), GRIN3B(170483), GRINA(66168)
rat ... AMPA 1(50592), GRIA2(29627), GRIA3(29628), GRIA4(29629), GRIN1(24408), GRIN2A(24409), GRIN2B(24410), GRIN2C(24411), GRIN2D(24412), GRIN3A(191573), GRIN3B(170796), GRINA(266668)

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Application

L-Cysteine hydrochloride has been used as a supplement in media to study the metabolic and sleep phenotypes of Drosophila melanogaster. It has also been used as one of the reagents for cell dissociation and single cell collection.

Biochem/physiol Actions

Cysteine (Cys) is a functional sulfur-containing aminoacid that regulates metabolism for growth, reproduction and immunity. It provides the disulfide linkage in proteins and is involved in the transport of sulfur. Cysteine is involved in the formation of hydrogen sulfide that functions as a signaling molecule. Cys residues are present at the catalytic sites of various enzymes.
NMDA glutamatergic receptor agonist that is also an agonist at AMPA glutamatergic receptors at high concentrations.
NMDA glutamatergic receptor agonist; AMPA glutamatergic receptor agonist at high concentrations.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000491590
0000491590
BCCN1841
BCCM8069
0000320736

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